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Volume of Plasma Cleared given Elimination Half Life Formula

GoVolume of Plasma Cleared of Drug given Rate at which Drug is Removed Formula

GoVolume of Plasma Cleared given Rate of Infusion Formula

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The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time. Check FAQs

CL = \frac{\ln (2) \cdot V d}{t b/2}

CL - Volume of Plasma Cleared?V_d - Volume of Distribution?t_b/2 - Elimination Half Life?

Volume of Plasma Cleared given Elimination Half Life Example

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Here is how the Volume of Plasma Cleared given Elimination Half Life equation looks like with Values.

Here is how the Volume of Plasma Cleared given Elimination Half Life equation looks like with Units.

Here is how the Volume of Plasma Cleared given Elimination Half Life equation looks like.

0.5199 = \frac{\ln (2) \cdot 9}{12}

0.5199L/s = \frac{\ln (2) \cdot 9L}{12s}

0.5199 = \frac{\ln (2) \cdot 9}{12}

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Volume of Plasma Cleared given Elimination Half Life Solution

Follow our step by step solution on how to calculate Volume of Plasma Cleared given Elimination Half Life?

FIRST Step Consider the formula

CL = \frac{\ln (2) \cdot V d}{t b/2}

Next Step Substitute values of Variables

∴

CL = \frac{\ln (2) \cdot 9L}{12s}

Next Step Convert Units

∴

CL = \frac{\ln (2) \cdot 0.009m³}{12s}

Next Step Prepare to Evaluate

∴

CL = \frac{\ln (2) \cdot 0.009}{12}

Next Step Evaluate

∴

CL = 0.000519860385419959m³/s

Next Step Convert to Output's Unit

∴

CL = 0.519860385419959L/s

LAST Step Rounding Answer

∴

CL = 0.5199L/s

Volume of Plasma Cleared given Elimination Half Life Formula Elements

Variables

Functions

Volume of Plasma Cleared

The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.

Symbol: CL

Measurement: Volumetric Flow RateUnit: L/s

Note: Value can be positive or negative.

Formulas to find Volume of Plasma Cleared

Volume of Distribution

The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

Symbol: V_d

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Volume of Distribution

Elimination Half Life

Elimination Half Life is the time required for the concentration of the drug to reach half of its original value.

Symbol: t_b/2

Measurement: TimeUnit: s

Note: Value should be greater than 0.

Formulas to find Elimination Half Life

The natural logarithm, also known as the logarithm to the base e, is the inverse function of the natural exponential function.

Syntax: ln(Number)

Other Formulas to find Volume of Plasma Cleared

Go Volume of Plasma Cleared of Drug given Rate at which Drug is Removed

CL = k e \cdot V d

Go Volume of Plasma Cleared given Rate of Infusion

CL = \frac{k in}{C ss}

Go Volume of Plasma Cleared given Area under Curve

CL = \frac{D}{AUC}

Other formulas in Volume of plasma cleared category

Go Fraction of Drug Unbound in Plasma given Plasma Volume

fu = (\frac{V d - V P}{V T}) \cdot fu t

How to Evaluate Volume of Plasma Cleared given Elimination Half Life?

Volume of Plasma Cleared given Elimination Half Life evaluator uses Volume of Plasma Cleared = (ln(2)*Volume of Distribution)/Elimination Half Life to evaluate the Volume of Plasma Cleared, The Volume of plasma cleared given elimination half life formula is defined as the direct relation with the apparent volume in which a drug is distributed and an inverse relationship with the time required for the concentration of the drug to reach half of its original value. Volume of Plasma Cleared is denoted by CL symbol.

How to evaluate Volume of Plasma Cleared given Elimination Half Life using this online evaluator? To use this online evaluator for Volume of Plasma Cleared given Elimination Half Life, enter Volume of Distribution (V_d) & Elimination Half Life (t_b/2) and hit the calculate button.

FAQs on Volume of Plasma Cleared given Elimination Half Life

What is the formula to find Volume of Plasma Cleared given Elimination Half Life?

The formula of Volume of Plasma Cleared given Elimination Half Life is expressed as Volume of Plasma Cleared = (ln(2)*Volume of Distribution)/Elimination Half Life. Here is an example- 519.8604 = (ln(2)*0.009)/12.

How to calculate Volume of Plasma Cleared given Elimination Half Life?

With Volume of Distribution (V_d) & Elimination Half Life (t_b/2) we can find Volume of Plasma Cleared given Elimination Half Life using the formula - Volume of Plasma Cleared = (ln(2)*Volume of Distribution)/Elimination Half Life. This formula also uses Natural Logarithm (ln) function(s).

What are the other ways to Calculate Volume of Plasma Cleared?

Here are the different ways to Calculate Volume of Plasma Cleared-

Volume of Plasma Cleared=Elimination Rate Constant*Volume of Distribution
Volume of Plasma Cleared=Rate of Infusion/Concentration of Drug
Volume of Plasma Cleared=Dose/Area Under Curve

Can the Volume of Plasma Cleared given Elimination Half Life be negative?

Yes, the Volume of Plasma Cleared given Elimination Half Life, measured in Volumetric Flow Rate can be negative.

Which unit is used to measure Volume of Plasma Cleared given Elimination Half Life?

Volume of Plasma Cleared given Elimination Half Life is usually measured using the Liter per Second[L/s] for Volumetric Flow Rate. Cubic Meter per Second[L/s], Cubic Meter per Day[L/s], Cubic Meter per Hour[L/s] are the few other units in which Volume of Plasma Cleared given Elimination Half Life can be measured.

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