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The Target Plasma Concentration is refer to the desired or optimal concentration of a drug in the bloodstream at a specific time after the administration. Check FAQs
Cp=(MDF%CLdrug)
Cp - Target Plasma Concentration?MD - Maintenance Dose?F% - Bioavailability Of drug dose?CLdrug - Drug Clearance?

Target Plasma Concentration given Maintenance Dose Example

With values
With units
Only example

Here is how the Target Plasma Concentration given Maintenance Dose equation looks like with Values.

Here is how the Target Plasma Concentration given Maintenance Dose equation looks like with Units.

Here is how the Target Plasma Concentration given Maintenance Dose equation looks like.

8.7E-6Edit=(70Edit0.9Edit2Edit)
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Target Plasma Concentration given Maintenance Dose Solution

Follow our step by step solution on how to calculate Target Plasma Concentration given Maintenance Dose?

FIRST Step Consider the formula
Cp=(MDF%CLdrug)
Next Step Substitute values of Variables
Cp=(70mg/h0.92m³/s)
Next Step Convert Units
Cp=(1.9E-8kg/s0.92m³/s)
Next Step Prepare to Evaluate
Cp=(1.9E-80.92)
Next Step Evaluate
Cp=8.74999999999998E-09kg/m³
Next Step Convert to Output's Unit
Cp=8.74999999999998E-06mg/L
LAST Step Rounding Answer
Cp=8.7E-6mg/L

Target Plasma Concentration given Maintenance Dose Formula Elements

Variables
Target Plasma Concentration
The Target Plasma Concentration is refer to the desired or optimal concentration of a drug in the bloodstream at a specific time after the administration.
Symbol: Cp
Measurement: Mass ConcentrationUnit: mg/L
Note: Value should be greater than 0.
Maintenance Dose
The Maintenance Dose is the dose of a drug that is administered on a regular basis to maintained a desired plasma concentration.
Symbol: MD
Measurement: Mass Flow RateUnit: mg/h
Note: Value should be greater than 0.
Bioavailability Of drug dose
The Bioavailability Of drug dose is describe the fraction or percentage of administration drug that reaches the systemic circulation in an unchanged and active form.
Symbol: F%
Measurement: NAUnit: Unitless
Note: Value can be positive or negative.
Drug Clearance
Drug Clearance is the rate at which a drug or its metabolites are removed from the body and systemic circulation.
Symbol: CLdrug
Measurement: Volumetric Flow RateUnit: m³/s
Note: Value can be positive or negative.

Other Formulas to find Target Plasma Concentration

​Go Target Plasma Concentration given Revised Dose
Cp=RDMcpssPDR
​Go Target Plasma Concentration given Loading Dose
Cp=LDF%Vd

Other formulas in Dose category

​Go Amount of drug administered given apparent volume
D=VdisCss
​Go Amount of drug in given volume of plasma
Css=DVdis
​Go Amount of drug administered given area under curve
D=CLAUC
​Go Dose given volume of distribution and area under curve
D=VdiskeAUC

How to Evaluate Target Plasma Concentration given Maintenance Dose?

Target Plasma Concentration given Maintenance Dose evaluator uses Target Plasma Concentration = (Maintenance Dose*Bioavailability Of drug dose/Drug Clearance) to evaluate the Target Plasma Concentration, The Target Plasma Concentration given Maintenance Dose formula is defined as the ratio of the product of the maintenance dose and bioavailaility of drug to the clearance of drug. Target Plasma Concentration is denoted by Cp symbol.

How to evaluate Target Plasma Concentration given Maintenance Dose using this online evaluator? To use this online evaluator for Target Plasma Concentration given Maintenance Dose, enter Maintenance Dose (MD), Bioavailability Of drug dose (F%) & Drug Clearance (CLdrug) and hit the calculate button.

FAQs on Target Plasma Concentration given Maintenance Dose

What is the formula to find Target Plasma Concentration given Maintenance Dose?
The formula of Target Plasma Concentration given Maintenance Dose is expressed as Target Plasma Concentration = (Maintenance Dose*Bioavailability Of drug dose/Drug Clearance). Here is an example- 0.00875 = (1.94444444444444E-08*0.9/2).
How to calculate Target Plasma Concentration given Maintenance Dose?
With Maintenance Dose (MD), Bioavailability Of drug dose (F%) & Drug Clearance (CLdrug) we can find Target Plasma Concentration given Maintenance Dose using the formula - Target Plasma Concentration = (Maintenance Dose*Bioavailability Of drug dose/Drug Clearance).
What are the other ways to Calculate Target Plasma Concentration?
Here are the different ways to Calculate Target Plasma Concentration-
  • Target Plasma Concentration=(Revised Dose*Measured Steady State Concentration Plasma)/Previous Rate of DoseOpenImg
  • Target Plasma Concentration=(Loading Dose*Bioavailability Of drug dose)/Volume Of Distribution doseOpenImg
Can the Target Plasma Concentration given Maintenance Dose be negative?
No, the Target Plasma Concentration given Maintenance Dose, measured in Mass Concentration cannot be negative.
Which unit is used to measure Target Plasma Concentration given Maintenance Dose?
Target Plasma Concentration given Maintenance Dose is usually measured using the Milligram per Liter[mg/L] for Mass Concentration. Kilogram per Cubic Meter[mg/L], Kilogram per Liter[mg/L], Gram per Liter[mg/L] are the few other units in which Target Plasma Concentration given Maintenance Dose can be measured.
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