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Substrate Concentration in Competitive Inhibition given Maximum Rate of System Formula

GoSubstrate Concentration of Competitive Inhibition of Enzyme Catalysis Formula

GoSubstrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Formula

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The Substrate Concentration is the number of moles of substrate per liter solution. Check FAQs

S = \frac{V 0 \cdot (K M \cdot (1 + (\frac{I}{K i})))}{V max - V 0}

S - Substrate Concentration?V₀ - Initial Reaction Rate?K_M - Michaelis Constant?I - Inhibitor Concentration?K_i - Enzyme Inhibitor Dissociation Constant?V_max - Maximum Rate?

Substrate Concentration in Competitive Inhibition given Maximum Rate of System Example

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Here is how the Substrate Concentration in Competitive Inhibition given Maximum Rate of System equation looks like with Values.

Here is how the Substrate Concentration in Competitive Inhibition given Maximum Rate of System equation looks like with Units.

Here is how the Substrate Concentration in Competitive Inhibition given Maximum Rate of System equation looks like.

0.0503 = \frac{0.45 \cdot (3 \cdot (1 + (\frac{9}{19})))}{40 - 0.45}

0.0503mol/L = \frac{0.45mol/L*s \cdot (3mol/L \cdot (1 + (\frac{9mol/L}{19mol/L})))}{40mol/L*s - 0.45mol/L*s}

0.0503 = \frac{0.45 \cdot (3 \cdot (1 + (\frac{9}{19})))}{40 - 0.45}

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Substrate Concentration in Competitive Inhibition given Maximum Rate of System Solution

Follow our step by step solution on how to calculate Substrate Concentration in Competitive Inhibition given Maximum Rate of System?

FIRST Step Consider the formula

S = \frac{V 0 \cdot (K M \cdot (1 + (\frac{I}{K i})))}{V max - V 0}

Next Step Substitute values of Variables

∴

S = \frac{0.45mol/L*s \cdot (3mol/L \cdot (1 + (\frac{9mol/L}{19mol/L})))}{40mol/L*s - 0.45mol/L*s}

Next Step Convert Units

∴

S = \frac{450mol/m³*s \cdot (3000mol/m³ \cdot (1 + (\frac{9000mol/m³}{19000mol/m³})))}{40000mol/m³*s - 450mol/m³*s}

Next Step Prepare to Evaluate

∴

S = \frac{450 \cdot (3000 \cdot (1 + (\frac{9000}{19000})))}{40000 - 450}

Next Step Evaluate

∴

S = 50.3027480204937mol/m³

Next Step Convert to Output's Unit

∴

S = 0.0503027480204937mol/L

LAST Step Rounding Answer

∴

S = 0.0503mol/L

Substrate Concentration in Competitive Inhibition given Maximum Rate of System Formula Elements

Variables

Substrate Concentration

The Substrate Concentration is the number of moles of substrate per liter solution.

Symbol: S

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Substrate Concentration

Initial Reaction Rate

The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.

Symbol: V₀

Measurement: Reaction RateUnit: mol/L*s

Note: Value can be positive or negative.

Formulas to find Initial Reaction Rate

Michaelis Constant

The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.

Symbol: K_M

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Michaelis Constant

Inhibitor Concentration

The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.

Symbol: I

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Inhibitor Concentration

Enzyme Inhibitor Dissociation Constant

The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

Symbol: K_i

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Enzyme Inhibitor Dissociation Constant

Maximum Rate

The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.

Symbol: V_max

Measurement: Reaction RateUnit: mol/L*s

Note: Value can be positive or negative.

Formulas to find Maximum Rate

Other Formulas to find Substrate Concentration

Go Substrate Concentration of Competitive Inhibition of Enzyme Catalysis

S = \frac{V 0 \cdot (K M \cdot (1 + (\frac{I}{K i})))}{(k 2 \cdot [E 0]) - V 0}

Go Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration

S = \frac{ES \cdot (K M \cdot (1 + (\frac{I}{K i})))}{([E 0]) - ES}

Go Substrate Concentration given Apparent value of Michaelis Menten Constant

S = \frac{Km app \cdot V 0}{V max - V 0}

Go Substrate Concentration given Modifying Factor in Michaelis Menten Equation

S = \frac{V 0 \cdot (\frac{α}{α'}) \cdot K M}{((\frac{1}{α'}) \cdot V max) - V 0}

Other formulas in Competitive Inhibitor category

Go Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition

Km app = \frac{S \cdot (V max - V 0)}{V 0}

Go Dissociation Constant for Competitive Inhibition of Enzyme Catalysis

K i = \frac{I}{(\frac{(\frac{k 2 \cdot [E 0] \cdot S}{V 0}) - S}{K M}) - 1}

Go Dissociation Constant in Competitive Inhibition given Maximum Rate of System

K i = \frac{I}{(\frac{(\frac{V max \cdot S}{V 0}) - S}{K M}) - 1}

Go Dissociation Constant of Enzyme given Modifying Factor of Enzyme

K ei = \frac{I}{α - 1}

How to Evaluate Substrate Concentration in Competitive Inhibition given Maximum Rate of System?

Substrate Concentration in Competitive Inhibition given Maximum Rate of System evaluator uses Substrate Concentration = (Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/(Maximum Rate-Initial Reaction Rate) to evaluate the Substrate Concentration, The Substrate concentration in competitive inhibition given maximum rate of system formula is defined as a plot of the reaction velocity (V0) associated with the concentration [S] of the substrate can then be used to determine values such as Vmax, initial velocity, and Km. Substrate Concentration is denoted by S symbol.

How to evaluate Substrate Concentration in Competitive Inhibition given Maximum Rate of System using this online evaluator? To use this online evaluator for Substrate Concentration in Competitive Inhibition given Maximum Rate of System, enter Initial Reaction Rate (V₀), Michaelis Constant (K_M), Inhibitor Concentration (I), Enzyme Inhibitor Dissociation Constant (K_i) & Maximum Rate (V_max) and hit the calculate button.

FAQs on Substrate Concentration in Competitive Inhibition given Maximum Rate of System

What is the formula to find Substrate Concentration in Competitive Inhibition given Maximum Rate of System?

The formula of Substrate Concentration in Competitive Inhibition given Maximum Rate of System is expressed as Substrate Concentration = (Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/(Maximum Rate-Initial Reaction Rate). Here is an example- 5E-5 = (450*(3000*(1+(9000/19000))))/(40000-450).

How to calculate Substrate Concentration in Competitive Inhibition given Maximum Rate of System?

With Initial Reaction Rate (V₀), Michaelis Constant (K_M), Inhibitor Concentration (I), Enzyme Inhibitor Dissociation Constant (K_i) & Maximum Rate (V_max) we can find Substrate Concentration in Competitive Inhibition given Maximum Rate of System using the formula - Substrate Concentration = (Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/(Maximum Rate-Initial Reaction Rate).

What are the other ways to Calculate Substrate Concentration?

Here are the different ways to Calculate Substrate Concentration-

Substrate Concentration=(Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Final Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)
Substrate Concentration=(Enzyme Substrate Complex Concentration*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Initial Enzyme Concentration)-Enzyme Substrate Complex Concentration)
Substrate Concentration=(Apparent Michaelis Constant*Initial Reaction Rate)/(Maximum Rate-Initial Reaction Rate)

Can the Substrate Concentration in Competitive Inhibition given Maximum Rate of System be negative?

Yes, the Substrate Concentration in Competitive Inhibition given Maximum Rate of System, measured in Molar Concentration can be negative.

Which unit is used to measure Substrate Concentration in Competitive Inhibition given Maximum Rate of System?

Substrate Concentration in Competitive Inhibition given Maximum Rate of System is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Substrate Concentration in Competitive Inhibition given Maximum Rate of System can be measured.

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Substrate Concentration in Competitive Inhibition given Maximum Rate of System Formula

​GoSubstrate Concentration of Competitive Inhibition of Enzyme Catalysis Formula

​GoSubstrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Formula

Substrate Concentration in Competitive Inhibition given Maximum Rate of System Example

Substrate Concentration in Competitive Inhibition given Maximum Rate of System Solution

Substrate Concentration in Competitive Inhibition given Maximum Rate of System Formula Elements

Other Formulas to find Substrate Concentration

Other formulas in Competitive Inhibitor category

How to Evaluate Substrate Concentration in Competitive Inhibition given Maximum Rate of System?

FAQs on Substrate Concentration in Competitive Inhibition given Maximum Rate of System

Variable Name

GoSubstrate Concentration of Competitive Inhibition of Enzyme Catalysis Formula

GoSubstrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Formula