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Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Formula

GoSubstrate Concentration of Competitive Inhibition of Enzyme Catalysis Formula

GoSubstrate Concentration in Competitive Inhibition given Maximum Rate of System Formula

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The Substrate Concentration is the number of moles of substrate per liter solution. Check FAQs

S = \frac{ES \cdot (K M \cdot (1 + (\frac{I}{K i})))}{([E 0]) - ES}

S - Substrate Concentration?ES - Enzyme Substrate Complex Concentration?K_M - Michaelis Constant?I - Inhibitor Concentration?K_i - Enzyme Inhibitor Dissociation Constant?[E₀] - Initial Enzyme Concentration?

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Example

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Here is how the Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration equation looks like with Values.

Here is how the Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration equation looks like with Units.

Here is how the Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration equation looks like.

0.4912 = \frac{10 \cdot (3 \cdot (1 + (\frac{9}{19})))}{(100) - 10}

0.4912mol/L = \frac{10mol/L \cdot (3mol/L \cdot (1 + (\frac{9mol/L}{19mol/L})))}{(100mol/L) - 10mol/L}

0.4912 = \frac{10 \cdot (3 \cdot (1 + (\frac{9}{19})))}{(100) - 10}

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Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Solution

Follow our step by step solution on how to calculate Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration?

FIRST Step Consider the formula

S = \frac{ES \cdot (K M \cdot (1 + (\frac{I}{K i})))}{([E 0]) - ES}

Next Step Substitute values of Variables

∴

S = \frac{10mol/L \cdot (3mol/L \cdot (1 + (\frac{9mol/L}{19mol/L})))}{(100mol/L) - 10mol/L}

Next Step Convert Units

∴

S = \frac{10000mol/m³ \cdot (3000mol/m³ \cdot (1 + (\frac{9000mol/m³}{19000mol/m³})))}{(100000mol/m³) - 10000mol/m³}

Next Step Prepare to Evaluate

∴

S = \frac{10000 \cdot (3000 \cdot (1 + (\frac{9000}{19000})))}{(100000) - 10000}

Next Step Evaluate

∴

S = 491.228070175439mol/m³

Next Step Convert to Output's Unit

∴

S = 0.491228070175439mol/L

LAST Step Rounding Answer

∴

S = 0.4912mol/L

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Formula Elements

Variables

Substrate Concentration

The Substrate Concentration is the number of moles of substrate per liter solution.

Symbol: S

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Substrate Concentration

Enzyme Substrate Complex Concentration

The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.

Symbol: ES

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Enzyme Substrate Complex Concentration

Michaelis Constant

The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.

Symbol: K_M

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Michaelis Constant

Inhibitor Concentration

The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.

Symbol: I

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Inhibitor Concentration

Enzyme Inhibitor Dissociation Constant

The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

Symbol: K_i

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Enzyme Inhibitor Dissociation Constant

Initial Enzyme Concentration

The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.

Symbol: [E₀]

Measurement: Molar ConcentrationUnit: mol/L

Note: Value should be greater than 0.

Formulas to find Initial Enzyme Concentration

Other Formulas to find Substrate Concentration

Go Substrate Concentration of Competitive Inhibition of Enzyme Catalysis

S = \frac{V 0 \cdot (K M \cdot (1 + (\frac{I}{K i})))}{(k 2 \cdot [E 0]) - V 0}

Go Substrate Concentration in Competitive Inhibition given Maximum Rate of System

S = \frac{V 0 \cdot (K M \cdot (1 + (\frac{I}{K i})))}{V max - V 0}

Go Substrate Concentration given Apparent value of Michaelis Menten Constant

S = \frac{Km app \cdot V 0}{V max - V 0}

Go Substrate Concentration given Modifying Factor in Michaelis Menten Equation

S = \frac{V 0 \cdot (\frac{α}{α'}) \cdot K M}{((\frac{1}{α'}) \cdot V max) - V 0}

Other formulas in Competitive Inhibitor category

Go Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition

Km app = \frac{S \cdot (V max - V 0)}{V 0}

Go Dissociation Constant for Competitive Inhibition of Enzyme Catalysis

K i = \frac{I}{(\frac{(\frac{k 2 \cdot [E 0] \cdot S}{V 0}) - S}{K M}) - 1}

Go Dissociation Constant in Competitive Inhibition given Maximum Rate of System

K i = \frac{I}{(\frac{(\frac{V max \cdot S}{V 0}) - S}{K M}) - 1}

Go Dissociation Constant of Enzyme given Modifying Factor of Enzyme

K ei = \frac{I}{α - 1}

How to Evaluate Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration?

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration evaluator uses Substrate Concentration = (Enzyme Substrate Complex Concentration*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Initial Enzyme Concentration)-Enzyme Substrate Complex Concentration) to evaluate the Substrate Concentration, The Substrate concentration in competitive inhibition given enzyme substrate complex concentration formula is defined as a plot of the reaction velocity (V0) associated with the concentration [S] of the substrate can then be used to determine values such as Vmax, initial velocity, and Km. Substrate Concentration is denoted by S symbol.

How to evaluate Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration using this online evaluator? To use this online evaluator for Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration, enter Enzyme Substrate Complex Concentration (ES), Michaelis Constant (K_M), Inhibitor Concentration (I), Enzyme Inhibitor Dissociation Constant (K_i) & Initial Enzyme Concentration ([E₀]) and hit the calculate button.

FAQs on Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration

What is the formula to find Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration?

The formula of Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration is expressed as Substrate Concentration = (Enzyme Substrate Complex Concentration*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Initial Enzyme Concentration)-Enzyme Substrate Complex Concentration). Here is an example- 0.000491 = (10000*(3000*(1+(9000/19000))))/((100000)-10000).

How to calculate Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration?

With Enzyme Substrate Complex Concentration (ES), Michaelis Constant (K_M), Inhibitor Concentration (I), Enzyme Inhibitor Dissociation Constant (K_i) & Initial Enzyme Concentration ([E₀]) we can find Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration using the formula - Substrate Concentration = (Enzyme Substrate Complex Concentration*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Initial Enzyme Concentration)-Enzyme Substrate Complex Concentration).

What are the other ways to Calculate Substrate Concentration?

Here are the different ways to Calculate Substrate Concentration-

Substrate Concentration=(Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Final Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)
Substrate Concentration=(Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/(Maximum Rate-Initial Reaction Rate)
Substrate Concentration=(Apparent Michaelis Constant*Initial Reaction Rate)/(Maximum Rate-Initial Reaction Rate)

Can the Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration be negative?

Yes, the Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration, measured in Molar Concentration can be negative.

Which unit is used to measure Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration?

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration can be measured.

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Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Formula

​GoSubstrate Concentration of Competitive Inhibition of Enzyme Catalysis Formula

​GoSubstrate Concentration in Competitive Inhibition given Maximum Rate of System Formula

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Example

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Solution

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration Formula Elements

Other Formulas to find Substrate Concentration

Other formulas in Competitive Inhibitor category

How to Evaluate Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration?

FAQs on Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration

Variable Name

GoSubstrate Concentration of Competitive Inhibition of Enzyme Catalysis Formula

GoSubstrate Concentration in Competitive Inhibition given Maximum Rate of System Formula