Secretion Rate of Drug Formula

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Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug. Check FAQs
Srate=(CLrCp)-(Frate)+(Rrate)
Srate - Secretion Rate of Drug?CLr - Renal Clearance?Cp - Plasma Concentration?Frate - Filtration Rate?Rrate - Reabsorption Rate of Drug?

Secretion Rate of Drug Example

With values
With units
Only example

Here is how the Secretion Rate of Drug equation looks like with Values.

Here is how the Secretion Rate of Drug equation looks like with Units.

Here is how the Secretion Rate of Drug equation looks like.

265200.5Edit=(15.6Edit17Edit)-(14Edit)+(14.5Edit)
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Secretion Rate of Drug Solution

Follow our step by step solution on how to calculate Secretion Rate of Drug?

FIRST Step Consider the formula
Srate=(CLrCp)-(Frate)+(Rrate)
Next Step Substitute values of Variables
Srate=(15.6mL/min17mol/L)-(14mL/min)+(14.5mL/min)
Next Step Convert Units
Srate=(2.6E-7m³/s17000mol/m³)-(2.3E-7m³/sec)+(2.4E-7m³/sec)
Next Step Prepare to Evaluate
Srate=(2.6E-717000)-(2.3E-7)+(2.4E-7)
Next Step Evaluate
Srate=0.00442000833333333m³/sec
LAST Step Convert to Output's Unit
Srate=265200.5mL/min

Secretion Rate of Drug Formula Elements

Variables
Secretion Rate of Drug
Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.
Symbol: Srate
Measurement: Glomerular Filtration RateUnit: mL/min
Note: Value should be greater than 0.
Renal Clearance
Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time.
Symbol: CLr
Measurement: Volumetric Flow RateUnit: mL/min
Note: Value should be greater than 0.
Plasma Concentration
Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.
Symbol: Cp
Measurement: Molar ConcentrationUnit: mol/L
Note: Value should be greater than 0.
Filtration Rate
Filtration Rate is the estimates of how much blood passes through the glomeruli each minute.
Symbol: Frate
Measurement: Glomerular Filtration RateUnit: mL/min
Note: Value should be greater than 0.
Reabsorption Rate of Drug
Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.
Symbol: Rrate
Measurement: Glomerular Filtration RateUnit: mL/min
Note: Value should be greater than 0.

Other formulas in Drug Content category

​Go Apparent Volume of Drug Distribution
Vd=DCss
​Go Absorption Half-Life of Drug
ta/2=ln(2)ka
​Go Drug Rate Entering Body
ka=ln(2)ta/2
​Go Rate of Infusion of Drug
kin=CLCss

How to Evaluate Secretion Rate of Drug?

Secretion Rate of Drug evaluator uses Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug) to evaluate the Secretion Rate of Drug, The Secretion Rate of Drug formula is defined as excretion of some substance such as hydrogen ions, creatinine, and drugs which will be removed from the blood through the peritubular capillary network into the collecting duct. Secretion Rate of Drug is denoted by Srate symbol.

How to evaluate Secretion Rate of Drug using this online evaluator? To use this online evaluator for Secretion Rate of Drug, enter Renal Clearance (CLr), Plasma Concentration (Cp), Filtration Rate (Frate) & Reabsorption Rate of Drug (Rrate) and hit the calculate button.

FAQs on Secretion Rate of Drug

What is the formula to find Secretion Rate of Drug?
The formula of Secretion Rate of Drug is expressed as Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug). Here is an example- 1.6E+13 = (2.6E-07*17000)-(2.33333333333333E-07)+(2.41666666666667E-07).
How to calculate Secretion Rate of Drug?
With Renal Clearance (CLr), Plasma Concentration (Cp), Filtration Rate (Frate) & Reabsorption Rate of Drug (Rrate) we can find Secretion Rate of Drug using the formula - Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug).
Can the Secretion Rate of Drug be negative?
No, the Secretion Rate of Drug, measured in Glomerular Filtration Rate cannot be negative.
Which unit is used to measure Secretion Rate of Drug?
Secretion Rate of Drug is usually measured using the Milliliter per Minute[mL/min] for Glomerular Filtration Rate. Cubic meter per second[mL/min] are the few other units in which Secretion Rate of Drug can be measured.
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