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The Reverse Rate Constant is defined as the rate constant for the backward reaction. Check FAQs
kr=(KMkf)-kcat
kr - Reverse Rate Constant?KM - Michaelis Constant?kf - Forward Rate Constant?kcat - Catalytic Rate Constant?

Reverse Rate Constant given Michaelis Constant Example

With values
With units
Only example

Here is how the Reverse Rate Constant given Michaelis Constant equation looks like with Values.

Here is how the Reverse Rate Constant given Michaelis Constant equation looks like with Units.

Here is how the Reverse Rate Constant given Michaelis Constant equation looks like.

20.6994Edit=(3Edit6.9Edit)-0.65Edit
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Reverse Rate Constant given Michaelis Constant Solution

Follow our step by step solution on how to calculate Reverse Rate Constant given Michaelis Constant?

FIRST Step Consider the formula
kr=(KMkf)-kcat
Next Step Substitute values of Variables
kr=(3mol/L6.9s⁻¹)-0.65s⁻¹
Next Step Convert Units
kr=(3000mol/m³6.9s⁻¹)-0.65s⁻¹
Next Step Prepare to Evaluate
kr=(30006.9)-0.65
Next Step Evaluate
kr=20699.35mol/m³*s
Next Step Convert to Output's Unit
kr=20.69935mol/L*s
LAST Step Rounding Answer
kr=20.6994mol/L*s

Reverse Rate Constant given Michaelis Constant Formula Elements

Variables
Reverse Rate Constant
The Reverse Rate Constant is defined as the rate constant for the backward reaction.
Symbol: kr
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Michaelis Constant
The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.
Symbol: KM
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Forward Rate Constant
The Forward Rate Constant is defined as the rate constant for the forward occurring reaction.
Symbol: kf
Measurement: First Order Reaction Rate ConstantUnit: s⁻¹
Note: Value can be positive or negative.
Catalytic Rate Constant
The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.
Symbol: kcat
Measurement: First Order Reaction Rate ConstantUnit: s⁻¹
Note: Value can be positive or negative.

Other Formulas to find Reverse Rate Constant

​Go Reverse Rate Constant in Enzymatic Reaction Mechanism
kr=kfS([E0]-ES)ES
​Go Reverse Rate Constant given Dissociation Rate Constant
kr=(KDkf)
​Go Reverse Rate Constant given Forward and Catalytic Rate Constants
kr=(kfESES)-kcat

Other formulas in Rate Constants of Enzymatic Reaction category

​Go Catalytic Rate Constant at Low Substrate Concentration
kcat=V0KM[E0]S
​Go Forward Rate Constant in Enzymatic Reaction mechanism
kf=krESS([E0]-ES)
​Go Dissociation Rate Constant in Enzymatic Reaction Mechanism
KD=krkf
​Go Forward Rate Constant given Dissociation Rate Constant
kf=(krKD)

How to Evaluate Reverse Rate Constant given Michaelis Constant?

Reverse Rate Constant given Michaelis Constant evaluator uses Reverse Rate Constant = (Michaelis Constant*Forward Rate Constant)-Catalytic Rate Constant to evaluate the Reverse Rate Constant, The Reverse rate constant given Michaelis constant formula is defined as the subtraction of catalytic rate constant from the product of Michaelis constant and forward rate constant of the enzymatic reaction mechanism. Reverse Rate Constant is denoted by kr symbol.

How to evaluate Reverse Rate Constant given Michaelis Constant using this online evaluator? To use this online evaluator for Reverse Rate Constant given Michaelis Constant, enter Michaelis Constant (KM), Forward Rate Constant (kf) & Catalytic Rate Constant (kcat) and hit the calculate button.

FAQs on Reverse Rate Constant given Michaelis Constant

What is the formula to find Reverse Rate Constant given Michaelis Constant?
The formula of Reverse Rate Constant given Michaelis Constant is expressed as Reverse Rate Constant = (Michaelis Constant*Forward Rate Constant)-Catalytic Rate Constant. Here is an example- 0.020699 = (3000*6.9)-0.65.
How to calculate Reverse Rate Constant given Michaelis Constant?
With Michaelis Constant (KM), Forward Rate Constant (kf) & Catalytic Rate Constant (kcat) we can find Reverse Rate Constant given Michaelis Constant using the formula - Reverse Rate Constant = (Michaelis Constant*Forward Rate Constant)-Catalytic Rate Constant.
What are the other ways to Calculate Reverse Rate Constant?
Here are the different ways to Calculate Reverse Rate Constant-
  • Reverse Rate Constant=(Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex ConcentrationOpenImg
  • Reverse Rate Constant=(Dissociation Rate Constant*Forward Rate Constant)OpenImg
  • Reverse Rate Constant=((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate ConstantOpenImg
Can the Reverse Rate Constant given Michaelis Constant be negative?
Yes, the Reverse Rate Constant given Michaelis Constant, measured in Reaction Rate can be negative.
Which unit is used to measure Reverse Rate Constant given Michaelis Constant?
Reverse Rate Constant given Michaelis Constant is usually measured using the Mole per Liter Second[mol/L*s] for Reaction Rate. Millimole per Liter Second[mol/L*s], Mole per Cubic Meter Second[mol/L*s] are the few other units in which Reverse Rate Constant given Michaelis Constant can be measured.
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