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Relative Bioavailability of Drug Formula

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Relative Bioavailability compares the bioavailability between two different dosage forms. Check FAQs

F rel = (\frac{AUC dosageA}{AUC dosageB}) \cdot (\frac{D B}{D A})

F_rel - Relative Bioavailability?AUC_dosageA - Area under curve Dosage A?AUC_dosageB - Area under curve Dosage B?D_B - Dose Type B?D_A - Dose Type A?

Relative Bioavailability of Drug Example

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Here is how the Relative Bioavailability of Drug equation looks like with Values.

Here is how the Relative Bioavailability of Drug equation looks like with Units.

Here is how the Relative Bioavailability of Drug equation looks like.

0.8593 = (\frac{1.141}{1.732}) \cdot (\frac{15}{11.5})

0.8593 = (\frac{1.141mol*s/L}{1.732mol*s/L}) \cdot (\frac{15mol}{11.5mol})

0.8593 = (\frac{1.141}{1.732}) \cdot (\frac{15}{11.5})

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Relative Bioavailability of Drug Solution

Follow our step by step solution on how to calculate Relative Bioavailability of Drug?

FIRST Step Consider the formula

F rel = (\frac{AUC dosageA}{AUC dosageB}) \cdot (\frac{D B}{D A})

Next Step Substitute values of Variables

∴

F rel = (\frac{1.141mol*s/L}{1.732mol*s/L}) \cdot (\frac{15mol}{11.5mol})

Next Step Convert Units

∴

F rel = (\frac{1141mol*s/m³}{1732mol*s/m³}) \cdot (\frac{15mol}{11.5mol})

Next Step Prepare to Evaluate

∴

F rel = (\frac{1141}{1732}) \cdot (\frac{15}{11.5})

Next Step Evaluate

∴

F rel = 0.859273019379456

LAST Step Rounding Answer

∴

F rel = 0.8593

Relative Bioavailability of Drug Formula Elements

Variables

Relative Bioavailability

Relative Bioavailability compares the bioavailability between two different dosage forms.

Symbol: F_rel

Measurement: NAUnit: Unitless

Note: Value should be greater than 0.

Formulas to find Relative Bioavailability

Area under curve Dosage A

The Area under curve Dosage A is the integral of the concentration-time curve for A form of dosage.

Symbol: AUC_dosageA

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value can be positive or negative.

Formulas to find Area under curve Dosage A

Area under curve Dosage B

The Area under curve Dosage B is the integral of the concentration-time curve for B form of dosage.

Symbol: AUC_dosageB

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value can be positive or negative.

Formulas to find Area under curve Dosage B

Dose Type B

Dose Type B is the amount of drug administered in B-type dosage form.

Symbol: D_B

Measurement: Amount of SubstanceUnit: mol

Note: Value should be greater than 0.

Formulas to find Dose Type B

Dose Type A

Dose Type A is the amount of drug administered in A-type dosage form.

Symbol: D_A

Measurement: Amount of SubstanceUnit: mol

Note: Value should be greater than 0.

Formulas to find Dose Type A

How to Evaluate Relative Bioavailability of Drug?

Relative Bioavailability of Drug evaluator uses Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A) to evaluate the Relative Bioavailability, The Relative bioavailability of drug formula is defined as the comparison of the bioavailability between two different dosage forms. Relative Bioavailability is denoted by F_rel symbol.

How to evaluate Relative Bioavailability of Drug using this online evaluator? To use this online evaluator for Relative Bioavailability of Drug, enter Area under curve Dosage A (AUC_dosageA), Area under curve Dosage B (AUC_dosageB), Dose Type B (D_B) & Dose Type A (D_A) and hit the calculate button.

FAQs on Relative Bioavailability of Drug

What is the formula to find Relative Bioavailability of Drug?

The formula of Relative Bioavailability of Drug is expressed as Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A). Here is an example- 0.859273 = (1141/1732)*(15/11.5).

How to calculate Relative Bioavailability of Drug?

With Area under curve Dosage A (AUC_dosageA), Area under curve Dosage B (AUC_dosageB), Dose Type B (D_B) & Dose Type A (D_A) we can find Relative Bioavailability of Drug using the formula - Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A).

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Relative Bioavailability of Drug Formula

Relative Bioavailability of Drug Example

Relative Bioavailability of Drug Solution

Relative Bioavailability of Drug Formula Elements

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How to Evaluate Relative Bioavailability of Drug?

FAQs on Relative Bioavailability of Drug

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