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Plasma Volume of Drug given Apparent Volume Formula

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Plasma Volume is the measurement in which a drug is distributed in blood plasma. Check FAQs

V P = V d - (V T \cdot (\frac{fu}{fu t}))

V_P - Plasma Volume?V_d - Volume of Distribution?V_T - Apparent Tissue Volume?fu - Fraction Unbound in Plasma?fu_t - Fraction Unbound in Tissue?

Plasma Volume of Drug given Apparent Volume Example

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With units

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Here is how the Plasma Volume of Drug given Apparent Volume equation looks like with Values.

Here is how the Plasma Volume of Drug given Apparent Volume equation looks like with Units.

Here is how the Plasma Volume of Drug given Apparent Volume equation looks like.

4.05 = 9 - (3.5 \cdot (\frac{0.99}{0.7}))

4.05L = 9L - (3.5L \cdot (\frac{0.99}{0.7}))

4.05 = 9 - (3.5 \cdot (\frac{0.99}{0.7}))

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Plasma Volume of Drug given Apparent Volume Solution

Follow our step by step solution on how to calculate Plasma Volume of Drug given Apparent Volume?

FIRST Step Consider the formula

V P = V d - (V T \cdot (\frac{fu}{fu t}))

Next Step Substitute values of Variables

∴

V P = 9L - (3.5L \cdot (\frac{0.99}{0.7}))

Next Step Convert Units

∴

V P = 0.009m³ - (0.0035m³ \cdot (\frac{0.99}{0.7}))

Next Step Prepare to Evaluate

∴

V P = 0.009 - (0.0035 \cdot (\frac{0.99}{0.7}))

Next Step Evaluate

∴

V P = 0.00405m³

LAST Step Convert to Output's Unit

∴

V P = 4.05L

Plasma Volume of Drug given Apparent Volume Formula Elements

Variables

Plasma Volume

Plasma Volume is the measurement in which a drug is distributed in blood plasma.

Symbol: V_P

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Plasma Volume

Volume of Distribution

The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

Symbol: V_d

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Volume of Distribution

Apparent Tissue Volume

Apparent Tissue Volume is defined as the ratio of the total amount of drug in the body to the concentration of drug in the body tissue.

Symbol: V_T

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Apparent Tissue Volume

Fraction Unbound in Plasma

Fraction Unbound in Plasma is defined as the systemically available fraction of a drug in blood plasma.

Symbol: fu

Measurement: NAUnit: Unitless

Note: Value should be greater than 0.

Formulas to find Fraction Unbound in Plasma

Fraction Unbound in Tissue

Fraction Unbound in Tissue is defined as the systemically available fraction of a drug in body tissue.

Symbol: fu_t

Measurement: NAUnit: Unitless

Note: Value should be greater than 0.

Formulas to find Fraction Unbound in Tissue

Other formulas in Plasma category

Go Apparent Tissue Volume given Plasma Volume and Apparent Volume

V T = (V d - V P) \cdot (\frac{fu t}{fu})

Go Peak through Fluctuation

%PTF = \frac{C max - C min}{C av}

Go Peak Plasma Concentration Given Peak through Fluctuation

C max = (%PTF \cdot C av) + C min

Go Lowest Plasma Concentration Given Peak through Fluctuation

C min = C max - (C av \cdot %PTF)

How to Evaluate Plasma Volume of Drug given Apparent Volume?

Plasma Volume of Drug given Apparent Volume evaluator uses Plasma Volume = Volume of Distribution-(Apparent Tissue Volume*(Fraction Unbound in Plasma/Fraction Unbound in Tissue)) to evaluate the Plasma Volume, The Plasma volume of drug given apparent volume formula is defined as the parameter relating drug concentration in plasma to drug amount in the body tissue. Plasma Volume is denoted by V_P symbol.

How to evaluate Plasma Volume of Drug given Apparent Volume using this online evaluator? To use this online evaluator for Plasma Volume of Drug given Apparent Volume, enter Volume of Distribution (V_d), Apparent Tissue Volume (V_T), Fraction Unbound in Plasma (fu) & Fraction Unbound in Tissue (fu_t) and hit the calculate button.

FAQs on Plasma Volume of Drug given Apparent Volume

What is the formula to find Plasma Volume of Drug given Apparent Volume?

The formula of Plasma Volume of Drug given Apparent Volume is expressed as Plasma Volume = Volume of Distribution-(Apparent Tissue Volume*(Fraction Unbound in Plasma/Fraction Unbound in Tissue)). Here is an example- 4050 = 0.009-(0.0035*(0.99/0.7)).

How to calculate Plasma Volume of Drug given Apparent Volume?

With Volume of Distribution (V_d), Apparent Tissue Volume (V_T), Fraction Unbound in Plasma (fu) & Fraction Unbound in Tissue (fu_t) we can find Plasma Volume of Drug given Apparent Volume using the formula - Plasma Volume = Volume of Distribution-(Apparent Tissue Volume*(Fraction Unbound in Plasma/Fraction Unbound in Tissue)).

Can the Plasma Volume of Drug given Apparent Volume be negative?

Yes, the Plasma Volume of Drug given Apparent Volume, measured in Volume can be negative.

Which unit is used to measure Plasma Volume of Drug given Apparent Volume?

Plasma Volume of Drug given Apparent Volume is usually measured using the Liter[L] for Volume. Cubic Meter[L], Cubic Centimeter[L], Cubic Millimeter[L] are the few other units in which Plasma Volume of Drug given Apparent Volume can be measured.

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Plasma Volume of Drug given Apparent Volume Formula

Plasma Volume of Drug given Apparent Volume Example

Plasma Volume of Drug given Apparent Volume Solution

Plasma Volume of Drug given Apparent Volume Formula Elements

Other formulas in Plasma category

How to Evaluate Plasma Volume of Drug given Apparent Volume?

FAQs on Plasma Volume of Drug given Apparent Volume

Variable Name