FormulaDen.com

Physics Chemistry Math Chemical Engineering Civil Electrical Electronics Electronics and Instrumentation Materials Science Mechanical Production Engineering Financial Health

Michaelis Constant in Presence of Uncompetitive Inhibitor Formula

Fx Copy

LaTeX Copy

The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system. Check FAQs

K M = \frac{S \cdot (V max - (V 0 \cdot α'))}{V 0}

K_M - Michaelis Constant?S - Substrate Concentration?V_max - Maximum Rate?V₀ - Initial Reaction Rate?α^' - Enzyme Substrate Modifying Factor?

Michaelis Constant in Presence of Uncompetitive Inhibitor Example

With values

With units

Only example

Here is how the Michaelis Constant in Presence of Uncompetitive Inhibitor equation looks like with Values.

Here is how the Michaelis Constant in Presence of Uncompetitive Inhibitor equation looks like with Units.

Here is how the Michaelis Constant in Presence of Uncompetitive Inhibitor equation looks like.

130.3333 = \frac{1.5 \cdot (40 - (0.45 \cdot 2))}{0.45}

130.3333mol/L = \frac{1.5mol/L \cdot (40mol/L*s - (0.45mol/L*s \cdot 2))}{0.45mol/L*s}

130.3333 = \frac{1.5 \cdot (40 - (0.45 \cdot 2))}{0.45}

Tip: Use pencil ( Pencil

) icon above to edit Input Values and Units.

Calculate

Recalculate

Solution

Copy

Reset

You are here -

Home » Category

Chemistry » Category

Chemical Kinetics » Category

Enzyme Kinetics » fx Michaelis Constant in Presence of Uncompetitive Inhibitor

Michaelis Constant in Presence of Uncompetitive Inhibitor Solution

Follow our step by step solution on how to calculate Michaelis Constant in Presence of Uncompetitive Inhibitor?

FIRST Step Consider the formula

K M = \frac{S \cdot (V max - (V 0 \cdot α'))}{V 0}

Next Step Substitute values of Variables

∴

K M = \frac{1.5mol/L \cdot (40mol/L*s - (0.45mol/L*s \cdot 2))}{0.45mol/L*s}

Next Step Convert Units

∴

K M = \frac{1500mol/m³ \cdot (40000mol/m³*s - (450mol/m³*s \cdot 2))}{450mol/m³*s}

Next Step Prepare to Evaluate

∴

K M = \frac{1500 \cdot (40000 - (450 \cdot 2))}{450}

Next Step Evaluate

∴

K M = 130333.333333333mol/m³

Next Step Convert to Output's Unit

∴

K M = 130.333333333333mol/L

LAST Step Rounding Answer

∴

K M = 130.3333mol/L

Michaelis Constant in Presence of Uncompetitive Inhibitor Formula Elements

Variables

Michaelis Constant

The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.

Symbol: K_M

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Michaelis Constant

Substrate Concentration

The Substrate Concentration is the number of moles of substrate per liter solution.

Symbol: S

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Substrate Concentration

Maximum Rate

The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.

Symbol: V_max

Measurement: Reaction RateUnit: mol/L*s

Note: Value can be positive or negative.

Formulas to find Maximum Rate

Initial Reaction Rate

The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.

Symbol: V₀

Measurement: Reaction RateUnit: mol/L*s

Note: Value can be positive or negative.

Formulas to find Initial Reaction Rate

Enzyme Substrate Modifying Factor

The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.

Symbol: α^'

Measurement: NAUnit: Unitless

Note: Value can be positive or negative.

Formulas to find Enzyme Substrate Modifying Factor

Other formulas in Uncompetitive Inhibitor category

Go Substrate Concentration in presence of Uncompetitive Inhibitor

S = \frac{K M \cdot V 0}{V max - (V 0 \cdot α')}

Go Initial Reaction Rate in presence of Uncompetitive Inhibitor

V 0 = \frac{V max \cdot S}{K M + (α' \cdot S)}

Go Maximum Reaction Rate in Presence of Uncompetitive Inhibitor

V max = \frac{V 0 \cdot (K M + (α' \cdot S))}{S}

Go Enzyme Substrate Modifying Factor in Presence of Uncompetitive Inhibitor

α' = \frac{(V max \cdot S) - (V 0 \cdot K M)}{V 0 \cdot S}

How to Evaluate Michaelis Constant in Presence of Uncompetitive Inhibitor?

Michaelis Constant in Presence of Uncompetitive Inhibitor evaluator uses Michaelis Constant = (Substrate Concentration*(Maximum Rate-(Initial Reaction Rate*Enzyme Substrate Modifying Factor)))/Initial Reaction Rate to evaluate the Michaelis Constant, The Michaelis constant in presence of uncompetitive inhibitor formula is defined by the altered Michaelis-Menten equation. Michaelis Constant is denoted by K_M symbol.

How to evaluate Michaelis Constant in Presence of Uncompetitive Inhibitor using this online evaluator? To use this online evaluator for Michaelis Constant in Presence of Uncompetitive Inhibitor, enter Substrate Concentration (S), Maximum Rate (V_max), Initial Reaction Rate (V₀) & Enzyme Substrate Modifying Factor (α^') and hit the calculate button.

FAQs on Michaelis Constant in Presence of Uncompetitive Inhibitor

What is the formula to find Michaelis Constant in Presence of Uncompetitive Inhibitor?

The formula of Michaelis Constant in Presence of Uncompetitive Inhibitor is expressed as Michaelis Constant = (Substrate Concentration*(Maximum Rate-(Initial Reaction Rate*Enzyme Substrate Modifying Factor)))/Initial Reaction Rate. Here is an example- 0.130333 = (1500*(40000-(450*2)))/450.

How to calculate Michaelis Constant in Presence of Uncompetitive Inhibitor?

With Substrate Concentration (S), Maximum Rate (V_max), Initial Reaction Rate (V₀) & Enzyme Substrate Modifying Factor (α^') we can find Michaelis Constant in Presence of Uncompetitive Inhibitor using the formula - Michaelis Constant = (Substrate Concentration*(Maximum Rate-(Initial Reaction Rate*Enzyme Substrate Modifying Factor)))/Initial Reaction Rate.

Can the Michaelis Constant in Presence of Uncompetitive Inhibitor be negative?

Yes, the Michaelis Constant in Presence of Uncompetitive Inhibitor, measured in Molar Concentration can be negative.

Which unit is used to measure Michaelis Constant in Presence of Uncompetitive Inhibitor?

Michaelis Constant in Presence of Uncompetitive Inhibitor is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Michaelis Constant in Presence of Uncompetitive Inhibitor can be measured.

Let Others Know

✖

Facebook

Twitter

Copied!

Michaelis Constant in Presence of Uncompetitive Inhibitor Formula

Michaelis Constant in Presence of Uncompetitive Inhibitor Example

Michaelis Constant in Presence of Uncompetitive Inhibitor Solution

Michaelis Constant in Presence of Uncompetitive Inhibitor Formula Elements

Other formulas in Uncompetitive Inhibitor category

How to Evaluate Michaelis Constant in Presence of Uncompetitive Inhibitor?

FAQs on Michaelis Constant in Presence of Uncompetitive Inhibitor

Variable Name