Lowest Plasma Concentration Given Peak through Fluctuation Formula

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Lowest Plasma Concentration is the minimum concentration that a drug reaches before the next dose is administered. Check FAQs
Cmin=Cmax-(Cav%PTF)
Cmin - Lowest Plasma Concentration?Cmax - Peak Plasma Concentration?Cav - Average Plasma Concentration?%PTF - Peak Through Fluctuation?

Lowest Plasma Concentration Given Peak through Fluctuation Example

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Here is how the Lowest Plasma Concentration Given Peak through Fluctuation equation looks like with Values.

Here is how the Lowest Plasma Concentration Given Peak through Fluctuation equation looks like with Units.

Here is how the Lowest Plasma Concentration Given Peak through Fluctuation equation looks like.

52.524Edit=60.9Edit-(20Edit0.4188Edit)
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Lowest Plasma Concentration Given Peak through Fluctuation Solution

Follow our step by step solution on how to calculate Lowest Plasma Concentration Given Peak through Fluctuation?

FIRST Step Consider the formula
Cmin=Cmax-(Cav%PTF)
Next Step Substitute values of Variables
Cmin=60.9mol/L-(20mol/L0.4188)
Next Step Convert Units
Cmin=60900mol/m³-(20000mol/m³0.4188)
Next Step Prepare to Evaluate
Cmin=60900-(200000.4188)
Next Step Evaluate
Cmin=52524mol/m³
LAST Step Convert to Output's Unit
Cmin=52.524mol/L

Lowest Plasma Concentration Given Peak through Fluctuation Formula Elements

Variables
Lowest Plasma Concentration
Lowest Plasma Concentration is the minimum concentration that a drug reaches before the next dose is administered.
Symbol: Cmin
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Peak Plasma Concentration
Peak Plasma Concentration is the maximum concentration of a drug after administration.
Symbol: Cmax
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Average Plasma Concentration
Average Plasma Concentration is the average concentration of the drug after administration and before the next dose is administered.
Symbol: Cav
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Peak Through Fluctuation
Peak Through Fluctuation is defined as the fluctuation within one dosing interval at a steady state.
Symbol: %PTF
Measurement: NAUnit: Unitless
Note: Value can be positive or negative.

Other formulas in Plasma category

​Go Plasma Volume of Drug given Apparent Volume
VP=Vd-(VT(fufut))
​Go Apparent Tissue Volume given Plasma Volume and Apparent Volume
VT=(Vd-VP)(futfu)
​Go Peak through Fluctuation
%PTF=Cmax-CminCav
​Go Peak Plasma Concentration Given Peak through Fluctuation
Cmax=(%PTFCav)+Cmin

How to Evaluate Lowest Plasma Concentration Given Peak through Fluctuation?

Lowest Plasma Concentration Given Peak through Fluctuation evaluator uses Lowest Plasma Concentration = Peak Plasma Concentration-(Average Plasma Concentration*Peak Through Fluctuation) to evaluate the Lowest Plasma Concentration, The Lowest Plasma Concentration Given Peak through Fluctuation formula is defined as the subtraction of average plasma concentration and peak fluctuation from the peak plasma concentration of drugs. Lowest Plasma Concentration is denoted by Cmin symbol.

How to evaluate Lowest Plasma Concentration Given Peak through Fluctuation using this online evaluator? To use this online evaluator for Lowest Plasma Concentration Given Peak through Fluctuation, enter Peak Plasma Concentration (Cmax), Average Plasma Concentration (Cav) & Peak Through Fluctuation (%PTF) and hit the calculate button.

FAQs on Lowest Plasma Concentration Given Peak through Fluctuation

What is the formula to find Lowest Plasma Concentration Given Peak through Fluctuation?
The formula of Lowest Plasma Concentration Given Peak through Fluctuation is expressed as Lowest Plasma Concentration = Peak Plasma Concentration-(Average Plasma Concentration*Peak Through Fluctuation). Here is an example- 0.052524 = 60900-(20000*0.4188).
How to calculate Lowest Plasma Concentration Given Peak through Fluctuation?
With Peak Plasma Concentration (Cmax), Average Plasma Concentration (Cav) & Peak Through Fluctuation (%PTF) we can find Lowest Plasma Concentration Given Peak through Fluctuation using the formula - Lowest Plasma Concentration = Peak Plasma Concentration-(Average Plasma Concentration*Peak Through Fluctuation).
Can the Lowest Plasma Concentration Given Peak through Fluctuation be negative?
Yes, the Lowest Plasma Concentration Given Peak through Fluctuation, measured in Molar Concentration can be negative.
Which unit is used to measure Lowest Plasma Concentration Given Peak through Fluctuation?
Lowest Plasma Concentration Given Peak through Fluctuation is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Lowest Plasma Concentration Given Peak through Fluctuation can be measured.
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