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The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place. Check FAQs
V0=VmaxS(αKM)+(α'S)
V0 - Initial Reaction Rate?Vmax - Maximum Rate?S - Substrate Concentration?α - Enzyme Modifying Factor?KM - Michaelis Constant?α' - Enzyme Substrate Modifying Factor?

Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation Example

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Here is how the Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation equation looks like with Values.

Here is how the Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation equation looks like with Units.

Here is how the Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation equation looks like.

3.3333Edit=40Edit1.5Edit(5Edit3Edit)+(2Edit1.5Edit)
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Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation Solution

Follow our step by step solution on how to calculate Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation?

FIRST Step Consider the formula
V0=VmaxS(αKM)+(α'S)
Next Step Substitute values of Variables
V0=40mol/L*s1.5mol/L(53mol/L)+(21.5mol/L)
Next Step Convert Units
V0=40000mol/m³*s1500mol/m³(53000mol/m³)+(21500mol/m³)
Next Step Prepare to Evaluate
V0=400001500(53000)+(21500)
Next Step Evaluate
V0=3333.33333333333mol/m³*s
Next Step Convert to Output's Unit
V0=3.33333333333333mol/L*s
LAST Step Rounding Answer
V0=3.3333mol/L*s

Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation Formula Elements

Variables
Initial Reaction Rate
The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Symbol: V0
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Maximum Rate
The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Symbol: Vmax
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Substrate Concentration
The Substrate Concentration is the number of moles of substrate per liter solution.
Symbol: S
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Enzyme Modifying Factor
The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme.
Symbol: α
Measurement: NAUnit: Unitless
Note: Value can be positive or negative.
Michaelis Constant
The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.
Symbol: KM
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Enzyme Substrate Modifying Factor
The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.
Symbol: α'
Measurement: NAUnit: Unitless
Note: Value can be positive or negative.

Other Formulas to find Initial Reaction Rate

​Go Initial Rate given Apparent value of Michaelis Menten Constant
V0=VmaxSKmapp+S

Other formulas in Michaelis Menten Kinetics Equation category

​Go Maximum Rate of System from Michaelis Menten Kinetics equation
Vmax=V0(KM+S)S
​Go Substrate Concentration from Michaelis Menten Kinetics Equation
S=KMV0Vmax-V0
​Go Michaelis Constant from Michaelis Menten kinetics equation
KM=S(Vmax-V0V0)
​Go Michaelis Constant given Catalytic Rate Constant and Initial Enzyme Concentration
KM=S((kcat[E0])-V0)V0

How to Evaluate Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation?

Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation evaluator uses Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)) to evaluate the Initial Reaction Rate, The Initial reaction rate of enzyme given modifying factor in Michaelis Menten equation formula is defined as the enzyme activity under various substrate and inhibitor concentrations, to obtain a modified Michaelis–Menten equation. Initial Reaction Rate is denoted by V0 symbol.

How to evaluate Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation using this online evaluator? To use this online evaluator for Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation, enter Maximum Rate (Vmax), Substrate Concentration (S), Enzyme Modifying Factor (α), Michaelis Constant (KM) & Enzyme Substrate Modifying Factor ') and hit the calculate button.

FAQs on Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation

What is the formula to find Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation?
The formula of Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation is expressed as Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)). Here is an example- 0.003333 = (40000*1500)/((5*3000)+(2*1500)).
How to calculate Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation?
With Maximum Rate (Vmax), Substrate Concentration (S), Enzyme Modifying Factor (α), Michaelis Constant (KM) & Enzyme Substrate Modifying Factor ') we can find Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation using the formula - Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)).
What are the other ways to Calculate Initial Reaction Rate?
Here are the different ways to Calculate Initial Reaction Rate-
  • Initial Reaction Rate=(Maximum Rate*Substrate Concentration)/(Apparent Michaelis Constant+Substrate Concentration)OpenImg
Can the Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation be negative?
Yes, the Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation, measured in Reaction Rate can be negative.
Which unit is used to measure Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation?
Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation is usually measured using the Mole per Liter Second[mol/L*s] for Reaction Rate. Millimole per Liter Second[mol/L*s], Mole per Cubic Meter Second[mol/L*s] are the few other units in which Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation can be measured.
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