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The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place. Check FAQs
V0=VmaxSKM+S
V0 - Initial Reaction Rate?Vmax - Maximum Rate?S - Substrate Concentration?KM - Michaelis Constant?

Initial Reaction Rate in Michaelis Menten kinetics Equation Example

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With units
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Here is how the Initial Reaction Rate in Michaelis Menten kinetics Equation equation looks like with Values.

Here is how the Initial Reaction Rate in Michaelis Menten kinetics Equation equation looks like with Units.

Here is how the Initial Reaction Rate in Michaelis Menten kinetics Equation equation looks like.

13.3333Edit=40Edit1.5Edit3Edit+1.5Edit
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Initial Reaction Rate in Michaelis Menten kinetics Equation Solution

Follow our step by step solution on how to calculate Initial Reaction Rate in Michaelis Menten kinetics Equation?

FIRST Step Consider the formula
V0=VmaxSKM+S
Next Step Substitute values of Variables
V0=40mol/L*s1.5mol/L3mol/L+1.5mol/L
Next Step Convert Units
V0=40000mol/m³*s1500mol/m³3000mol/m³+1500mol/m³
Next Step Prepare to Evaluate
V0=4000015003000+1500
Next Step Evaluate
V0=13333.3333333333mol/m³*s
Next Step Convert to Output's Unit
V0=13.3333333333333mol/L*s
LAST Step Rounding Answer
V0=13.3333mol/L*s

Initial Reaction Rate in Michaelis Menten kinetics Equation Formula Elements

Variables
Initial Reaction Rate
The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Symbol: V0
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Maximum Rate
The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Symbol: Vmax
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Substrate Concentration
The Substrate Concentration is the number of moles of substrate per liter solution.
Symbol: S
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Michaelis Constant
The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.
Symbol: KM
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.

Other Formulas to find Initial Reaction Rate

​Go Initial Reaction Rate given Catalytic Rate Constant and Initial Enzyme Concentration
V0=kcat[E0]SKM+S
​Go Initial Reaction Rate at Low Substrate Concentration
V0=kcat[E0]SKM
​Go Initial Reaction Rate at Low Substrate Concentration terms of Maximum Rate
V0=VmaxSKM
​Go Initial Reaction Rate given Catalytic Rate Constant and Dissociation Rate Constants
V0=kcat[E0]SKD+S

Other formulas in Enzyme Kinetics category

​Go Maximum Rate of System at Low Substrate Concentration
Vmax=V0KMS
​Go Initial Reaction Rate given Dissociation Rate Constant
VDRC=VmaxSKD+S
​Go Maximum Rate given Dissociation Rate Constant
Vmax_DRC=V0(KD+S)S
​Go Modifying Factor of Enzyme Substrate Complex
α'=1+(IKi')

How to Evaluate Initial Reaction Rate in Michaelis Menten kinetics Equation?

Initial Reaction Rate in Michaelis Menten kinetics Equation evaluator uses Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/(Michaelis Constant+Substrate Concentration) to evaluate the Initial Reaction Rate, The Initial reaction rate in Michaelis Menten kinetics equation formula is defined as the relation with the maximum rate achieved by the system and the concentration of a substrate. Initial Reaction Rate is denoted by V0 symbol.

How to evaluate Initial Reaction Rate in Michaelis Menten kinetics Equation using this online evaluator? To use this online evaluator for Initial Reaction Rate in Michaelis Menten kinetics Equation, enter Maximum Rate (Vmax), Substrate Concentration (S) & Michaelis Constant (KM) and hit the calculate button.

FAQs on Initial Reaction Rate in Michaelis Menten kinetics Equation

What is the formula to find Initial Reaction Rate in Michaelis Menten kinetics Equation?
The formula of Initial Reaction Rate in Michaelis Menten kinetics Equation is expressed as Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/(Michaelis Constant+Substrate Concentration). Here is an example- 0.013333 = (40000*1500)/(3000+1500).
How to calculate Initial Reaction Rate in Michaelis Menten kinetics Equation?
With Maximum Rate (Vmax), Substrate Concentration (S) & Michaelis Constant (KM) we can find Initial Reaction Rate in Michaelis Menten kinetics Equation using the formula - Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/(Michaelis Constant+Substrate Concentration).
What are the other ways to Calculate Initial Reaction Rate?
Here are the different ways to Calculate Initial Reaction Rate-
  • Initial Reaction Rate=(Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/(Michaelis Constant+Substrate Concentration)OpenImg
  • Initial Reaction Rate=(Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Michaelis ConstantOpenImg
  • Initial Reaction Rate=(Maximum Rate*Substrate Concentration)/Michaelis ConstantOpenImg
Can the Initial Reaction Rate in Michaelis Menten kinetics Equation be negative?
Yes, the Initial Reaction Rate in Michaelis Menten kinetics Equation, measured in Reaction Rate can be negative.
Which unit is used to measure Initial Reaction Rate in Michaelis Menten kinetics Equation?
Initial Reaction Rate in Michaelis Menten kinetics Equation is usually measured using the Mole per Liter Second[mol/L*s] for Reaction Rate. Millimole per Liter Second[mol/L*s], Mole per Cubic Meter Second[mol/L*s] are the few other units in which Initial Reaction Rate in Michaelis Menten kinetics Equation can be measured.
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