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Initial Rate of System of Competitive Inhibition of Enzyme Catalysis Formula

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The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place. Check FAQs

V 0 = \frac{k 2 \cdot [E 0] \cdot S}{K M \cdot (1 + (\frac{I}{K i})) + S}

V₀ - Initial Reaction Rate?k₂ - Final Rate Constant?[E₀] - Initial Enzyme Concentration?S - Substrate Concentration?K_M - Michaelis Constant?I - Inhibitor Concentration?K_i - Enzyme Inhibitor Dissociation Constant?

Initial Rate of System of Competitive Inhibition of Enzyme Catalysis Example

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Here is how the Initial Rate of System of Competitive Inhibition of Enzyme Catalysis equation looks like with Values.

Here is how the Initial Rate of System of Competitive Inhibition of Enzyme Catalysis equation looks like with Units.

Here is how the Initial Rate of System of Competitive Inhibition of Enzyme Catalysis equation looks like.

582.6667 = \frac{23 \cdot 100 \cdot 1.5}{3 \cdot (1 + (\frac{9}{19})) + 1.5}

582.6667mol/L*s = \frac{23s⁻¹ \cdot 100mol/L \cdot 1.5mol/L}{3mol/L \cdot (1 + (\frac{9mol/L}{19mol/L})) + 1.5mol/L}

582.6667 = \frac{23 \cdot 100 \cdot 1.5}{3 \cdot (1 + (\frac{9}{19})) + 1.5}

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Enzyme Kinetics » fx Initial Rate of System of Competitive Inhibition of Enzyme Catalysis

Initial Rate of System of Competitive Inhibition of Enzyme Catalysis Solution

Follow our step by step solution on how to calculate Initial Rate of System of Competitive Inhibition of Enzyme Catalysis?

FIRST Step Consider the formula

V 0 = \frac{k 2 \cdot [E 0] \cdot S}{K M \cdot (1 + (\frac{I}{K i})) + S}

Next Step Substitute values of Variables

∴

V 0 = \frac{23s⁻¹ \cdot 100mol/L \cdot 1.5mol/L}{3mol/L \cdot (1 + (\frac{9mol/L}{19mol/L})) + 1.5mol/L}

Next Step Convert Units

∴

V 0 = \frac{23s⁻¹ \cdot 100000mol/m³ \cdot 1500mol/m³}{3000mol/m³ \cdot (1 + (\frac{9000mol/m³}{19000mol/m³})) + 1500mol/m³}

Next Step Prepare to Evaluate

∴

V 0 = \frac{23 \cdot 100000 \cdot 1500}{3000 \cdot (1 + (\frac{9000}{19000})) + 1500}

Next Step Evaluate

∴

V 0 = 582666.666666667mol/m³*s

Next Step Convert to Output's Unit

∴

V 0 = 582.666666666667mol/L*s

LAST Step Rounding Answer

∴

V 0 = 582.6667mol/L*s

Initial Rate of System of Competitive Inhibition of Enzyme Catalysis Formula Elements

Variables

Initial Reaction Rate

The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.

Symbol: V₀

Measurement: Reaction RateUnit: mol/L*s

Note: Value can be positive or negative.

Formulas to find Initial Reaction Rate

Final Rate Constant

The Final Rate Constant is the rate constant when the enzyme-substrate complex on reaction with inhibitor is converted into the enzyme catalyst and product.

Symbol: k₂

Measurement: First Order Reaction Rate ConstantUnit: s⁻¹

Note: Value can be positive or negative.

Formulas to find Final Rate Constant

Initial Enzyme Concentration

The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.

Symbol: [E₀]

Measurement: Molar ConcentrationUnit: mol/L

Note: Value should be greater than 0.

Formulas to find Initial Enzyme Concentration

Substrate Concentration

The Substrate Concentration is the number of moles of substrate per liter solution.

Symbol: S

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Substrate Concentration

Michaelis Constant

The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.

Symbol: K_M

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Michaelis Constant

Inhibitor Concentration

The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.

Symbol: I

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Inhibitor Concentration

Enzyme Inhibitor Dissociation Constant

The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

Symbol: K_i

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Enzyme Inhibitor Dissociation Constant

Other formulas in Competitive Inhibitor category

Go Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition

Km app = \frac{S \cdot (V max - V 0)}{V 0}

Go Substrate Concentration of Competitive Inhibition of Enzyme Catalysis

S = \frac{V 0 \cdot (K M \cdot (1 + (\frac{I}{K i})))}{(k 2 \cdot [E 0]) - V 0}

How to Evaluate Initial Rate of System of Competitive Inhibition of Enzyme Catalysis?

Initial Rate of System of Competitive Inhibition of Enzyme Catalysis evaluator uses Initial Reaction Rate = (Final Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration) to evaluate the Initial Reaction Rate, The Initial rate of system of competitive inhibition of enzyme catalysis formula is defined as a plot of the reaction velocity (V0) associated with the concentration [S] of the substrate can then be used to determine values such as Vmax, initial velocity, and Km. Initial Reaction Rate is denoted by V₀ symbol.

How to evaluate Initial Rate of System of Competitive Inhibition of Enzyme Catalysis using this online evaluator? To use this online evaluator for Initial Rate of System of Competitive Inhibition of Enzyme Catalysis, enter Final Rate Constant (k₂), Initial Enzyme Concentration ([E₀]), Substrate Concentration (S), Michaelis Constant (K_M), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (K_i) and hit the calculate button.

FAQs on Initial Rate of System of Competitive Inhibition of Enzyme Catalysis

What is the formula to find Initial Rate of System of Competitive Inhibition of Enzyme Catalysis?

The formula of Initial Rate of System of Competitive Inhibition of Enzyme Catalysis is expressed as Initial Reaction Rate = (Final Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration). Here is an example- 0.582667 = (23*100000*1500)/(3000*(1+(9000/19000))+1500).

How to calculate Initial Rate of System of Competitive Inhibition of Enzyme Catalysis?

With Final Rate Constant (k₂), Initial Enzyme Concentration ([E₀]), Substrate Concentration (S), Michaelis Constant (K_M), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (K_i) we can find Initial Rate of System of Competitive Inhibition of Enzyme Catalysis using the formula - Initial Reaction Rate = (Final Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration).

Can the Initial Rate of System of Competitive Inhibition of Enzyme Catalysis be negative?

Yes, the Initial Rate of System of Competitive Inhibition of Enzyme Catalysis, measured in Reaction Rate can be negative.

Which unit is used to measure Initial Rate of System of Competitive Inhibition of Enzyme Catalysis?

Initial Rate of System of Competitive Inhibition of Enzyme Catalysis is usually measured using the Mole per Liter Second[mol/L*s] for Reaction Rate. Millimole per Liter Second[mol/L*s], Mole per Cubic Meter Second[mol/L*s] are the few other units in which Initial Rate of System of Competitive Inhibition of Enzyme Catalysis can be measured.

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Initial Rate of System of Competitive Inhibition of Enzyme Catalysis Formula

Initial Rate of System of Competitive Inhibition of Enzyme Catalysis Example

Initial Rate of System of Competitive Inhibition of Enzyme Catalysis Solution

Initial Rate of System of Competitive Inhibition of Enzyme Catalysis Formula Elements

Other formulas in Competitive Inhibitor category

How to Evaluate Initial Rate of System of Competitive Inhibition of Enzyme Catalysis?

FAQs on Initial Rate of System of Competitive Inhibition of Enzyme Catalysis

Variable Name