Initial Rate in Competitive Inhibition given Maximum Rate of system Formula

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Initial Reaction Rate in CI is defined as the initial speed at which a chemical reaction takes place. Check FAQs
VCI=VmaxSKM(1+(IKi))+S
VCI - Initial Reaction Rate in CI?Vmax - Maximum Rate?S - Substrate Concentration?KM - Michaelis Constant?I - Inhibitor Concentration?Ki - Enzyme Inhibitor Dissociation Constant?

Initial Rate in Competitive Inhibition given Maximum Rate of system Example

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Here is how the Initial Rate in Competitive Inhibition given Maximum Rate of system equation looks like with Values.

Here is how the Initial Rate in Competitive Inhibition given Maximum Rate of system equation looks like with Units.

Here is how the Initial Rate in Competitive Inhibition given Maximum Rate of system equation looks like.

10.1333Edit=40Edit1.5Edit3Edit(1+(9Edit19Edit))+1.5Edit
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Initial Rate in Competitive Inhibition given Maximum Rate of system Solution

Follow our step by step solution on how to calculate Initial Rate in Competitive Inhibition given Maximum Rate of system?

FIRST Step Consider the formula
VCI=VmaxSKM(1+(IKi))+S
Next Step Substitute values of Variables
VCI=40mol/L*s1.5mol/L3mol/L(1+(9mol/L19mol/L))+1.5mol/L
Next Step Convert Units
VCI=40000mol/m³*s1500mol/m³3000mol/m³(1+(9000mol/m³19000mol/m³))+1500mol/m³
Next Step Prepare to Evaluate
VCI=4000015003000(1+(900019000))+1500
Next Step Evaluate
VCI=10133.3333333333mol/m³*s
Next Step Convert to Output's Unit
VCI=10.1333333333333mol/L*s
LAST Step Rounding Answer
VCI=10.1333mol/L*s

Initial Rate in Competitive Inhibition given Maximum Rate of system Formula Elements

Variables
Initial Reaction Rate in CI
Initial Reaction Rate in CI is defined as the initial speed at which a chemical reaction takes place.
Symbol: VCI
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Maximum Rate
The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Symbol: Vmax
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Substrate Concentration
The Substrate Concentration is the number of moles of substrate per liter solution.
Symbol: S
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Michaelis Constant
The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.
Symbol: KM
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Inhibitor Concentration
The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Symbol: I
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Enzyme Inhibitor Dissociation Constant
The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.
Symbol: Ki
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.

Other formulas in Competitive Inhibitor category

​Go Modifying Factor of Enzyme Substrate Complex
α'=1+(IKi')
​Go Initial Rate of System given Rate Constant and Enzyme Substrate Complex Concentration
VRC=k2ES
​Go Initial Reaction Rate given Dissociation Rate Constant
VDRC=VmaxSKD+S
​Go Maximum Rate given Dissociation Rate Constant
Vmax_DRC=V0(KD+S)S

How to Evaluate Initial Rate in Competitive Inhibition given Maximum Rate of system?

Initial Rate in Competitive Inhibition given Maximum Rate of system evaluator uses Initial Reaction Rate in CI = (Maximum Rate*Substrate Concentration)/(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration) to evaluate the Initial Reaction Rate in CI, The Initial rate in competitive inhibition given maximum rate of system formula is defined as a plot of the reaction velocity (V0) associated with the concentration [S] of the substrate can then be used to determine values such as Vmax, initial velocity, and Km. Initial Reaction Rate in CI is denoted by VCI symbol.

How to evaluate Initial Rate in Competitive Inhibition given Maximum Rate of system using this online evaluator? To use this online evaluator for Initial Rate in Competitive Inhibition given Maximum Rate of system, enter Maximum Rate (Vmax), Substrate Concentration (S), Michaelis Constant (KM), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (Ki) and hit the calculate button.

FAQs on Initial Rate in Competitive Inhibition given Maximum Rate of system

What is the formula to find Initial Rate in Competitive Inhibition given Maximum Rate of system?
The formula of Initial Rate in Competitive Inhibition given Maximum Rate of system is expressed as Initial Reaction Rate in CI = (Maximum Rate*Substrate Concentration)/(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration). Here is an example- 0.010133 = (40000*1500)/(3000*(1+(9000/19000))+1500).
How to calculate Initial Rate in Competitive Inhibition given Maximum Rate of system?
With Maximum Rate (Vmax), Substrate Concentration (S), Michaelis Constant (KM), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (Ki) we can find Initial Rate in Competitive Inhibition given Maximum Rate of system using the formula - Initial Reaction Rate in CI = (Maximum Rate*Substrate Concentration)/(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration).
Can the Initial Rate in Competitive Inhibition given Maximum Rate of system be negative?
Yes, the Initial Rate in Competitive Inhibition given Maximum Rate of system, measured in Reaction Rate can be negative.
Which unit is used to measure Initial Rate in Competitive Inhibition given Maximum Rate of system?
Initial Rate in Competitive Inhibition given Maximum Rate of system is usually measured using the Mole per Liter Second[mol/L*s] for Reaction Rate. Millimole per Liter Second[mol/L*s], Mole per Cubic Meter Second[mol/L*s] are the few other units in which Initial Rate in Competitive Inhibition given Maximum Rate of system can be measured.
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