Initial Enzyme Concentration in presence of Noncompetitive Inhibitor Formula

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The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction. Check FAQs
[E0]=(E0app(1+(IKi)))
[E0] - Initial Enzyme Concentration?E0app - Apparent Initial Enzyme Concentration?I - Inhibitor Concentration?Ki - Enzyme Inhibitor Dissociation Constant?

Initial Enzyme Concentration in presence of Noncompetitive Inhibitor Example

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Here is how the Initial Enzyme Concentration in presence of Noncompetitive Inhibitor equation looks like with Values.

Here is how the Initial Enzyme Concentration in presence of Noncompetitive Inhibitor equation looks like with Units.

Here is how the Initial Enzyme Concentration in presence of Noncompetitive Inhibitor equation looks like.

0.0884Edit=(0.06Edit(1+(9Edit19Edit)))
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Initial Enzyme Concentration in presence of Noncompetitive Inhibitor Solution

Follow our step by step solution on how to calculate Initial Enzyme Concentration in presence of Noncompetitive Inhibitor?

FIRST Step Consider the formula
[E0]=(E0app(1+(IKi)))
Next Step Substitute values of Variables
[E0]=(0.06mol/L(1+(9mol/L19mol/L)))
Next Step Convert Units
[E0]=(60mol/m³(1+(9000mol/m³19000mol/m³)))
Next Step Prepare to Evaluate
[E0]=(60(1+(900019000)))
Next Step Evaluate
[E0]=88.4210526315789mol/m³
Next Step Convert to Output's Unit
[E0]=0.0884210526315789mol/L
LAST Step Rounding Answer
[E0]=0.0884mol/L

Initial Enzyme Concentration in presence of Noncompetitive Inhibitor Formula Elements

Variables
Initial Enzyme Concentration
The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.
Symbol: [E0]
Measurement: Molar ConcentrationUnit: mol/L
Note: Value should be greater than 0.
Apparent Initial Enzyme Concentration
The Apparent Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction in the presence of a non-competitive inhibitor.
Symbol: E0app
Measurement: Molar ConcentrationUnit: mol/L
Note: Value should be greater than 0.
Inhibitor Concentration
The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Symbol: I
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Enzyme Inhibitor Dissociation Constant
The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.
Symbol: Ki
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.

Other formulas in Noncompetitive Inhibitor category

​Go Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor
E0app=([E0]1+(IKi))
​Go Apparent Maximum Rate in presence of Noncompetitive Inhibitor
Vmaxapp=(Vmax1+(IKi))
​Go Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant
Kmapp=KM(1+(IKi))
​Go Dissociation Constant given Apparent Initial Enzyme Concentration
Ki=(I([E0]E0app)-1)

How to Evaluate Initial Enzyme Concentration in presence of Noncompetitive Inhibitor?

Initial Enzyme Concentration in presence of Noncompetitive Inhibitor evaluator uses Initial Enzyme Concentration = (Apparent Initial Enzyme Concentration*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))) to evaluate the Initial Enzyme Concentration, The Initial enzyme concentration in presence of noncompetitive inhibitor formula is defined as relation with the apparent initial enzyme concentration, inhibitor concentration and with dissociation constant. Initial Enzyme Concentration is denoted by [E0] symbol.

How to evaluate Initial Enzyme Concentration in presence of Noncompetitive Inhibitor using this online evaluator? To use this online evaluator for Initial Enzyme Concentration in presence of Noncompetitive Inhibitor, enter Apparent Initial Enzyme Concentration (E0app), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (Ki) and hit the calculate button.

FAQs on Initial Enzyme Concentration in presence of Noncompetitive Inhibitor

What is the formula to find Initial Enzyme Concentration in presence of Noncompetitive Inhibitor?
The formula of Initial Enzyme Concentration in presence of Noncompetitive Inhibitor is expressed as Initial Enzyme Concentration = (Apparent Initial Enzyme Concentration*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))). Here is an example- 8.8E-5 = (60*(1+(9000/19000))).
How to calculate Initial Enzyme Concentration in presence of Noncompetitive Inhibitor?
With Apparent Initial Enzyme Concentration (E0app), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (Ki) we can find Initial Enzyme Concentration in presence of Noncompetitive Inhibitor using the formula - Initial Enzyme Concentration = (Apparent Initial Enzyme Concentration*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))).
Can the Initial Enzyme Concentration in presence of Noncompetitive Inhibitor be negative?
No, the Initial Enzyme Concentration in presence of Noncompetitive Inhibitor, measured in Molar Concentration cannot be negative.
Which unit is used to measure Initial Enzyme Concentration in presence of Noncompetitive Inhibitor?
Initial Enzyme Concentration in presence of Noncompetitive Inhibitor is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Initial Enzyme Concentration in presence of Noncompetitive Inhibitor can be measured.
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