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Enzyme Concentration Initially is defined as the concentration of enzyme at the start of the reaction. Check FAQs
[Einitial]=ES(KD+S)S
[Einitial] - Enzyme Concentration Initially?ES - Enzyme Substrate Complex Concentration?KD - Dissociation Rate Constant?S - Substrate Concentration?

Initial Enzyme Concentration given Dissociation Rate Constant Example

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Here is how the Initial Enzyme Concentration given Dissociation Rate Constant equation looks like with Values.

Here is how the Initial Enzyme Concentration given Dissociation Rate Constant equation looks like with Units.

Here is how the Initial Enzyme Concentration given Dissociation Rate Constant equation looks like.

48Edit=10Edit(5.7Edit+1.5Edit)1.5Edit
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Initial Enzyme Concentration given Dissociation Rate Constant Solution

Follow our step by step solution on how to calculate Initial Enzyme Concentration given Dissociation Rate Constant?

FIRST Step Consider the formula
[Einitial]=ES(KD+S)S
Next Step Substitute values of Variables
[Einitial]=10mol/L(5.7mol/L+1.5mol/L)1.5mol/L
Next Step Convert Units
[Einitial]=10000mol/m³(5700mol/m³+1500mol/m³)1500mol/m³
Next Step Prepare to Evaluate
[Einitial]=10000(5700+1500)1500
Next Step Evaluate
[Einitial]=48000mol/m³
LAST Step Convert to Output's Unit
[Einitial]=48mol/L

Initial Enzyme Concentration given Dissociation Rate Constant Formula Elements

Variables
Enzyme Concentration Initially
Enzyme Concentration Initially is defined as the concentration of enzyme at the start of the reaction.
Symbol: [Einitial]
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Enzyme Substrate Complex Concentration
The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.
Symbol: ES
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Dissociation Rate Constant
The Dissociation Rate Constant is the ratio of reverse and forward rate constant.
Symbol: KD
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Substrate Concentration
The Substrate Concentration is the number of moles of substrate per liter solution.
Symbol: S
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.

Other Formulas to find Enzyme Concentration Initially

​Go Initial Concentration of Enzyme in presence of Inhibitor by Enzyme Conservation Law
[Einitial]=(E+ES+EI)
​Go Initial Enzyme Concentration if Substrate Concentration is Higher than Michaelis Constant
[Einitial]=Vmaxkcat

Other formulas in Complex Concentration category

​Go Modifying Factor of Enzyme Substrate Complex
α'=1+(IKi')
​Go Initial Rate of System given Rate Constant and Enzyme Substrate Complex Concentration
VRC=k2ES
​Go Initial Reaction Rate given Dissociation Rate Constant
VDRC=VmaxSKD+S
​Go Maximum Rate given Dissociation Rate Constant
Vmax_DRC=V0(KD+S)S

How to Evaluate Initial Enzyme Concentration given Dissociation Rate Constant?

Initial Enzyme Concentration given Dissociation Rate Constant evaluator uses Enzyme Concentration Initially = (Enzyme Substrate Complex Concentration*(Dissociation Rate Constant+Substrate Concentration))/(Substrate Concentration) to evaluate the Enzyme Concentration Initially, The Initial enzyme concentration given dissociation rate constant formula is defined as the relation with the dissociation rate constant and the concentration of enzyme and substrate. Enzyme Concentration Initially is denoted by [Einitial] symbol.

How to evaluate Initial Enzyme Concentration given Dissociation Rate Constant using this online evaluator? To use this online evaluator for Initial Enzyme Concentration given Dissociation Rate Constant, enter Enzyme Substrate Complex Concentration (ES), Dissociation Rate Constant (KD) & Substrate Concentration (S) and hit the calculate button.

FAQs on Initial Enzyme Concentration given Dissociation Rate Constant

What is the formula to find Initial Enzyme Concentration given Dissociation Rate Constant?
The formula of Initial Enzyme Concentration given Dissociation Rate Constant is expressed as Enzyme Concentration Initially = (Enzyme Substrate Complex Concentration*(Dissociation Rate Constant+Substrate Concentration))/(Substrate Concentration). Here is an example- 0.048 = (10000*(5700+1500))/(1500).
How to calculate Initial Enzyme Concentration given Dissociation Rate Constant?
With Enzyme Substrate Complex Concentration (ES), Dissociation Rate Constant (KD) & Substrate Concentration (S) we can find Initial Enzyme Concentration given Dissociation Rate Constant using the formula - Enzyme Concentration Initially = (Enzyme Substrate Complex Concentration*(Dissociation Rate Constant+Substrate Concentration))/(Substrate Concentration).
What are the other ways to Calculate Enzyme Concentration Initially?
Here are the different ways to Calculate Enzyme Concentration Initially-
  • Enzyme Concentration Initially=(Catalyst Concentration+Enzyme Substrate Complex Concentration+Enzyme Inhibitor Complex Concentration)OpenImg
  • Enzyme Concentration Initially=Maximum Rate/Catalytic Rate ConstantOpenImg
Can the Initial Enzyme Concentration given Dissociation Rate Constant be negative?
Yes, the Initial Enzyme Concentration given Dissociation Rate Constant, measured in Molar Concentration can be negative.
Which unit is used to measure Initial Enzyme Concentration given Dissociation Rate Constant?
Initial Enzyme Concentration given Dissociation Rate Constant is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Initial Enzyme Concentration given Dissociation Rate Constant can be measured.
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