Inhibitor Concentration in presence of Noncompetitive Inhibitor Formula

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The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system. Check FAQs
I=((VmaxVmaxapp)-1)Ki
I - Inhibitor Concentration?Vmax - Maximum Rate?Vmaxapp - Apparent Maximum Rate?Ki - Enzyme Inhibitor Dissociation Constant?

Inhibitor Concentration in presence of Noncompetitive Inhibitor Example

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Here is how the Inhibitor Concentration in presence of Noncompetitive Inhibitor equation looks like with Values.

Here is how the Inhibitor Concentration in presence of Noncompetitive Inhibitor equation looks like with Units.

Here is how the Inhibitor Concentration in presence of Noncompetitive Inhibitor equation looks like.

17.1905Edit=((40Edit21Edit)-1)19Edit
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Inhibitor Concentration in presence of Noncompetitive Inhibitor Solution

Follow our step by step solution on how to calculate Inhibitor Concentration in presence of Noncompetitive Inhibitor?

FIRST Step Consider the formula
I=((VmaxVmaxapp)-1)Ki
Next Step Substitute values of Variables
I=((40mol/L*s21mol/L*s)-1)19mol/L
Next Step Convert Units
I=((40000mol/m³*s21000mol/m³*s)-1)19000mol/m³
Next Step Prepare to Evaluate
I=((4000021000)-1)19000
Next Step Evaluate
I=17190.4761904762mol/m³
Next Step Convert to Output's Unit
I=17.1904761904762mol/L
LAST Step Rounding Answer
I=17.1905mol/L

Inhibitor Concentration in presence of Noncompetitive Inhibitor Formula Elements

Variables
Inhibitor Concentration
The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Symbol: I
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Maximum Rate
The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Symbol: Vmax
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Apparent Maximum Rate
Apparent Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration in presence of non-competitive inhibitor.
Symbol: Vmaxapp
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Enzyme Inhibitor Dissociation Constant
The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.
Symbol: Ki
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.

Other formulas in Noncompetitive Inhibitor category

​Go Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor
E0app=([E0]1+(IKi))
​Go Apparent Maximum Rate in presence of Noncompetitive Inhibitor
Vmaxapp=(Vmax1+(IKi))
​Go Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant
Kmapp=KM(1+(IKi))
​Go Dissociation Constant given Apparent Initial Enzyme Concentration
Ki=(I([E0]E0app)-1)

How to Evaluate Inhibitor Concentration in presence of Noncompetitive Inhibitor?

Inhibitor Concentration in presence of Noncompetitive Inhibitor evaluator uses Inhibitor Concentration = ((Maximum Rate/Apparent Maximum Rate)-1)*Enzyme Inhibitor Dissociation Constant to evaluate the Inhibitor Concentration, The Inhibitor concentration in presence of noncompetitive inhibitor formula is defined as relation with the maximum rate of the system, apparent maximum rate, and with dissociation constant. Inhibitor Concentration is denoted by I symbol.

How to evaluate Inhibitor Concentration in presence of Noncompetitive Inhibitor using this online evaluator? To use this online evaluator for Inhibitor Concentration in presence of Noncompetitive Inhibitor, enter Maximum Rate (Vmax), Apparent Maximum Rate (Vmaxapp) & Enzyme Inhibitor Dissociation Constant (Ki) and hit the calculate button.

FAQs on Inhibitor Concentration in presence of Noncompetitive Inhibitor

What is the formula to find Inhibitor Concentration in presence of Noncompetitive Inhibitor?
The formula of Inhibitor Concentration in presence of Noncompetitive Inhibitor is expressed as Inhibitor Concentration = ((Maximum Rate/Apparent Maximum Rate)-1)*Enzyme Inhibitor Dissociation Constant. Here is an example- 0.01719 = ((40000/21000)-1)*19000.
How to calculate Inhibitor Concentration in presence of Noncompetitive Inhibitor?
With Maximum Rate (Vmax), Apparent Maximum Rate (Vmaxapp) & Enzyme Inhibitor Dissociation Constant (Ki) we can find Inhibitor Concentration in presence of Noncompetitive Inhibitor using the formula - Inhibitor Concentration = ((Maximum Rate/Apparent Maximum Rate)-1)*Enzyme Inhibitor Dissociation Constant.
Can the Inhibitor Concentration in presence of Noncompetitive Inhibitor be negative?
Yes, the Inhibitor Concentration in presence of Noncompetitive Inhibitor, measured in Molar Concentration can be negative.
Which unit is used to measure Inhibitor Concentration in presence of Noncompetitive Inhibitor?
Inhibitor Concentration in presence of Noncompetitive Inhibitor is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Inhibitor Concentration in presence of Noncompetitive Inhibitor can be measured.
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