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Inhibitor Concentration given Apparent Michaelis Menten Constant Formula

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The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system. Check FAQs

I = ((\frac{Km app}{K M}) - 1) \cdot K i

I - Inhibitor Concentration?Km^app - Apparent Michaelis Constant?K_M - Michaelis Constant?K_i - Enzyme Inhibitor Dissociation Constant?

Inhibitor Concentration given Apparent Michaelis Menten Constant Example

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Here is how the Inhibitor Concentration given Apparent Michaelis Menten Constant equation looks like with Values.

Here is how the Inhibitor Concentration given Apparent Michaelis Menten Constant equation looks like with Units.

Here is how the Inhibitor Concentration given Apparent Michaelis Menten Constant equation looks like.

57 = ((\frac{12}{3}) - 1) \cdot 19

57mol/L = ((\frac{12mol/L}{3mol/L}) - 1) \cdot 19mol/L

57 = ((\frac{12}{3}) - 1) \cdot 19

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Inhibitor Concentration given Apparent Michaelis Menten Constant Solution

Follow our step by step solution on how to calculate Inhibitor Concentration given Apparent Michaelis Menten Constant?

FIRST Step Consider the formula

I = ((\frac{Km app}{K M}) - 1) \cdot K i

Next Step Substitute values of Variables

∴

I = ((\frac{12mol/L}{3mol/L}) - 1) \cdot 19mol/L

Next Step Convert Units

∴

I = ((\frac{12000mol/m³}{3000mol/m³}) - 1) \cdot 19000mol/m³

Next Step Prepare to Evaluate

∴

I = ((\frac{12000}{3000}) - 1) \cdot 19000

Next Step Evaluate

∴

I = 57000mol/m³

LAST Step Convert to Output's Unit

∴

I = 57mol/L

Inhibitor Concentration given Apparent Michaelis Menten Constant Formula Elements

Variables

Inhibitor Concentration

The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.

Symbol: I

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Inhibitor Concentration

Apparent Michaelis Constant

The Apparent Michaelis Constant is defined as the Michaelis–Menten constant in the presence of a competitive inhibitor.

Symbol: Km^app

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Apparent Michaelis Constant

Michaelis Constant

The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.

Symbol: K_M

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Michaelis Constant

Enzyme Inhibitor Dissociation Constant

The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

Symbol: K_i

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Enzyme Inhibitor Dissociation Constant

Other formulas in Michaelis Menten Kinetics Equation category

Go Maximum Rate of System from Michaelis Menten Kinetics equation

V max = \frac{V 0 \cdot (K M + S)}{S}

Go Substrate Concentration from Michaelis Menten Kinetics Equation

S = \frac{K M \cdot V 0}{V max - V 0}

Go Michaelis Constant from Michaelis Menten kinetics equation

K M = S \cdot (\frac{V max - V 0}{V 0})

Go Michaelis Constant given Catalytic Rate Constant and Initial Enzyme Concentration

K M = \frac{S \cdot ((k cat \cdot [E 0]) - V 0)}{V 0}

How to Evaluate Inhibitor Concentration given Apparent Michaelis Menten Constant?

Inhibitor Concentration given Apparent Michaelis Menten Constant evaluator uses Inhibitor Concentration = ((Apparent Michaelis Constant/Michaelis Constant)-1)*Enzyme Inhibitor Dissociation Constant to evaluate the Inhibitor Concentration, The Inhibitor concentration given apparent Michaelis Menten constant formula is defined as the relation with Michaelis constant and apparent value of Michaelis constant and with inhibitor's dissociation constant. Inhibitor Concentration is denoted by I symbol.

How to evaluate Inhibitor Concentration given Apparent Michaelis Menten Constant using this online evaluator? To use this online evaluator for Inhibitor Concentration given Apparent Michaelis Menten Constant, enter Apparent Michaelis Constant (Km^app), Michaelis Constant (K_M) & Enzyme Inhibitor Dissociation Constant (K_i) and hit the calculate button.

FAQs on Inhibitor Concentration given Apparent Michaelis Menten Constant

What is the formula to find Inhibitor Concentration given Apparent Michaelis Menten Constant?

The formula of Inhibitor Concentration given Apparent Michaelis Menten Constant is expressed as Inhibitor Concentration = ((Apparent Michaelis Constant/Michaelis Constant)-1)*Enzyme Inhibitor Dissociation Constant. Here is an example- 0.057 = ((12000/3000)-1)*19000.

How to calculate Inhibitor Concentration given Apparent Michaelis Menten Constant?

With Apparent Michaelis Constant (Km^app), Michaelis Constant (K_M) & Enzyme Inhibitor Dissociation Constant (K_i) we can find Inhibitor Concentration given Apparent Michaelis Menten Constant using the formula - Inhibitor Concentration = ((Apparent Michaelis Constant/Michaelis Constant)-1)*Enzyme Inhibitor Dissociation Constant.

Can the Inhibitor Concentration given Apparent Michaelis Menten Constant be negative?

Yes, the Inhibitor Concentration given Apparent Michaelis Menten Constant, measured in Molar Concentration can be negative.

Which unit is used to measure Inhibitor Concentration given Apparent Michaelis Menten Constant?

Inhibitor Concentration given Apparent Michaelis Menten Constant is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Inhibitor Concentration given Apparent Michaelis Menten Constant can be measured.

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Inhibitor Concentration given Apparent Michaelis Menten Constant Formula

Inhibitor Concentration given Apparent Michaelis Menten Constant Example

Inhibitor Concentration given Apparent Michaelis Menten Constant Solution

Inhibitor Concentration given Apparent Michaelis Menten Constant Formula Elements

Other formulas in Michaelis Menten Kinetics Equation category

How to Evaluate Inhibitor Concentration given Apparent Michaelis Menten Constant?

FAQs on Inhibitor Concentration given Apparent Michaelis Menten Constant

Variable Name