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Fraction of Drug Unbound in Tissue given Apparent Tissue Volume Formula

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Fraction Unbound in Tissue is defined as the systemically available fraction of a drug in body tissue. Check FAQs

fu t = \frac{fu \cdot V T}{V d - V P}

fu_t - Fraction Unbound in Tissue?fu - Fraction Unbound in Plasma?V_T - Apparent Tissue Volume?V_d - Volume of Distribution?V_P - Plasma Volume?

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume Example

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Here is how the Fraction of Drug Unbound in Tissue given Apparent Tissue Volume equation looks like with Values.

Here is how the Fraction of Drug Unbound in Tissue given Apparent Tissue Volume equation looks like with Units.

Here is how the Fraction of Drug Unbound in Tissue given Apparent Tissue Volume equation looks like.

0.8663 = \frac{0.99 \cdot 3.5}{9 - 5}

0.8663 = \frac{0.99 \cdot 3.5L}{9L - 5L}

0.8663 = \frac{0.99 \cdot 3.5}{9 - 5}

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Drug Content » fx Fraction of Drug Unbound in Tissue given Apparent Tissue Volume

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume Solution

Follow our step by step solution on how to calculate Fraction of Drug Unbound in Tissue given Apparent Tissue Volume?

FIRST Step Consider the formula

fu t = \frac{fu \cdot V T}{V d - V P}

Next Step Substitute values of Variables

∴

fu t = \frac{0.99 \cdot 3.5L}{9L - 5L}

Next Step Convert Units

∴

fu t = \frac{0.99 \cdot 0.0035m³}{0.009m³ - 0.005m³}

Next Step Prepare to Evaluate

∴

fu t = \frac{0.99 \cdot 0.0035}{0.009 - 0.005}

Next Step Evaluate

∴

fu t = 0.86625

LAST Step Rounding Answer

∴

fu t = 0.8663

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume Formula Elements

Variables

Fraction Unbound in Tissue

Fraction Unbound in Tissue is defined as the systemically available fraction of a drug in body tissue.

Symbol: fu_t

Measurement: NAUnit: Unitless

Note: Value should be greater than 0.

Formulas to find Fraction Unbound in Tissue

Fraction Unbound in Plasma

Fraction Unbound in Plasma is defined as the systemically available fraction of a drug in blood plasma.

Symbol: fu

Measurement: NAUnit: Unitless

Note: Value should be greater than 0.

Formulas to find Fraction Unbound in Plasma

Apparent Tissue Volume

Apparent Tissue Volume is defined as the ratio of the total amount of drug in the body to the concentration of drug in the body tissue.

Symbol: V_T

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Apparent Tissue Volume

Volume of Distribution

The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

Symbol: V_d

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Volume of Distribution

Plasma Volume

Plasma Volume is the measurement in which a drug is distributed in blood plasma.

Symbol: V_P

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Plasma Volume

How to Evaluate Fraction of Drug Unbound in Tissue given Apparent Tissue Volume?

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume evaluator uses Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume) to evaluate the Fraction Unbound in Tissue, The Fraction of drug unbound in tissue given apparent tissue volume formula is defined as the systemically available fraction of a drug in blood plasma with respect to body tissue. Fraction Unbound in Tissue is denoted by fu_t symbol.

How to evaluate Fraction of Drug Unbound in Tissue given Apparent Tissue Volume using this online evaluator? To use this online evaluator for Fraction of Drug Unbound in Tissue given Apparent Tissue Volume, enter Fraction Unbound in Plasma (fu), Apparent Tissue Volume (V_T), Volume of Distribution (V_d) & Plasma Volume (V_P) and hit the calculate button.

FAQs on Fraction of Drug Unbound in Tissue given Apparent Tissue Volume

What is the formula to find Fraction of Drug Unbound in Tissue given Apparent Tissue Volume?

The formula of Fraction of Drug Unbound in Tissue given Apparent Tissue Volume is expressed as Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume). Here is an example- 0.86625 = (0.99*0.0035)/(0.009-0.005).

How to calculate Fraction of Drug Unbound in Tissue given Apparent Tissue Volume?

With Fraction Unbound in Plasma (fu), Apparent Tissue Volume (V_T), Volume of Distribution (V_d) & Plasma Volume (V_P) we can find Fraction of Drug Unbound in Tissue given Apparent Tissue Volume using the formula - Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume).

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Fraction of Drug Unbound in Tissue given Apparent Tissue Volume Formula

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume Example

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume Solution

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume Formula Elements

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How to Evaluate Fraction of Drug Unbound in Tissue given Apparent Tissue Volume?

FAQs on Fraction of Drug Unbound in Tissue given Apparent Tissue Volume

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