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Elimination Rate Constant of Drug Formula

GoElimination Rate Constant given Area under Curve Formula

GoElimination Rate Constant given Volume of Plasma Cleared Formula

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Elimination Rate Constant is the rate at which a drug is removed from the body. Check FAQs

k e = \frac{\ln (2)}{t b/2}

k_e - Elimination Rate Constant?t_b/2 - Elimination Half Life?

Elimination Rate Constant of Drug Example

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With units

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Here is how the Elimination Rate Constant of Drug equation looks like with Values.

Here is how the Elimination Rate Constant of Drug equation looks like with Units.

Here is how the Elimination Rate Constant of Drug equation looks like.

207.9442 = \frac{\ln (2)}{12}

207.9442h⁻¹ = \frac{\ln (2)}{12s}

207.9442 = \frac{\ln (2)}{12}

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Elimination Rate Constant of Drug Solution

Follow our step by step solution on how to calculate Elimination Rate Constant of Drug?

FIRST Step Consider the formula

k e = \frac{\ln (2)}{t b/2}

Next Step Substitute values of Variables

∴

k e = \frac{\ln (2)}{12s}

Next Step Prepare to Evaluate

∴

k e = \frac{\ln (2)}{12}

Next Step Evaluate

∴

k e = 0.0577622650466621s⁻¹

Next Step Convert to Output's Unit

∴

k e = 207.944154167984h⁻¹

LAST Step Rounding Answer

∴

k e = 207.9442h⁻¹

Elimination Rate Constant of Drug Formula Elements

Variables

Functions

Elimination Rate Constant

Elimination Rate Constant is the rate at which a drug is removed from the body.

Symbol: k_e

Measurement: First Order Reaction Rate ConstantUnit: h⁻¹

Note: Value should be greater than 0.

Formulas to find Elimination Rate Constant

Elimination Half Life

Elimination Half Life is the time required for the concentration of the drug to reach half of its original value.

Symbol: t_b/2

Measurement: TimeUnit: s

Note: Value should be greater than 0.

Formulas to find Elimination Half Life

The natural logarithm, also known as the logarithm to the base e, is the inverse function of the natural exponential function.

Syntax: ln(Number)

Other Formulas to find Elimination Rate Constant

Go Elimination Rate Constant given Area under Curve

k e = \frac{D}{AUC \cdot V d}

Go Elimination Rate Constant given Volume of Plasma Cleared

k e = \frac{CL}{V d}

Other formulas in Elimination Rate Constant category

Go Elimination Half Life given Volume of Plasma Cleared

t b/2 = \frac{\ln (2) \cdot V d}{CL}

Go Elimination Half Life of Drug

t b/2 = \frac{\ln (2)}{k e}

Go Total Clearance of Body

CL total = CL hepatic + CL renal + CL pulmonary + CL other

How to Evaluate Elimination Rate Constant of Drug?

Elimination Rate Constant of Drug evaluator uses Elimination Rate Constant = ln(2)/Elimination Half Life to evaluate the Elimination Rate Constant, The Elimination rate constant of drug is defined as the inverse relationship with the time required for the concentration of the drug to reach half of its original value. Elimination Rate Constant is denoted by k_e symbol.

How to evaluate Elimination Rate Constant of Drug using this online evaluator? To use this online evaluator for Elimination Rate Constant of Drug, enter Elimination Half Life (t_b/2) and hit the calculate button.

FAQs on Elimination Rate Constant of Drug

What is the formula to find Elimination Rate Constant of Drug?

The formula of Elimination Rate Constant of Drug is expressed as Elimination Rate Constant = ln(2)/Elimination Half Life. Here is an example- 748599 = ln(2)/12.

How to calculate Elimination Rate Constant of Drug?

With Elimination Half Life (t_b/2) we can find Elimination Rate Constant of Drug using the formula - Elimination Rate Constant = ln(2)/Elimination Half Life. This formula also uses Natural Logarithm (ln) function(s).

What are the other ways to Calculate Elimination Rate Constant?

Here are the different ways to Calculate Elimination Rate Constant-

Elimination Rate Constant=Dose/(Area Under Curve*Volume of Distribution)
Elimination Rate Constant=Volume of Plasma Cleared/Volume of Distribution

Can the Elimination Rate Constant of Drug be negative?

No, the Elimination Rate Constant of Drug, measured in First Order Reaction Rate Constant cannot be negative.

Which unit is used to measure Elimination Rate Constant of Drug?

Elimination Rate Constant of Drug is usually measured using the 1 Per Hour[h⁻¹] for First Order Reaction Rate Constant. 1 Per Second[h⁻¹], 1 Per Millisecond[h⁻¹], 1 Per Day[h⁻¹] are the few other units in which Elimination Rate Constant of Drug can be measured.

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