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Elimination Rate Constant given Volume of Plasma Cleared Formula

GoElimination Rate Constant given Area under Curve Formula

GoElimination Rate Constant of Drug Formula

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Elimination Rate Constant is the rate at which a drug is removed from the body. Check FAQs

k e = \frac{CL}{V d}

k_e - Elimination Rate Constant?CL - Volume of Plasma Cleared?V_d - Volume of Distribution?

Elimination Rate Constant given Volume of Plasma Cleared Example

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Here is how the Elimination Rate Constant given Volume of Plasma Cleared equation looks like with Values.

Here is how the Elimination Rate Constant given Volume of Plasma Cleared equation looks like with Units.

Here is how the Elimination Rate Constant given Volume of Plasma Cleared equation looks like.

192 = \frac{0.48}{9}

192h⁻¹ = \frac{0.48L/s}{9L}

192 = \frac{0.48}{9}

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Elimination Rate Constant given Volume of Plasma Cleared Solution

Follow our step by step solution on how to calculate Elimination Rate Constant given Volume of Plasma Cleared?

FIRST Step Consider the formula

k e = \frac{CL}{V d}

Next Step Substitute values of Variables

∴

k e = \frac{0.48L/s}{9L}

Next Step Convert Units

∴

k e = \frac{0.0005m³/s}{0.009m³}

Next Step Prepare to Evaluate

∴

k e = \frac{0.0005}{0.009}

Next Step Evaluate

∴

k e = 0.0533333333333333s⁻¹

LAST Step Convert to Output's Unit

∴

k e = 192h⁻¹

Elimination Rate Constant given Volume of Plasma Cleared Formula Elements

Variables

Elimination Rate Constant

Elimination Rate Constant is the rate at which a drug is removed from the body.

Symbol: k_e

Measurement: First Order Reaction Rate ConstantUnit: h⁻¹

Note: Value should be greater than 0.

Formulas to find Elimination Rate Constant

Volume of Plasma Cleared

The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.

Symbol: CL

Measurement: Volumetric Flow RateUnit: L/s

Note: Value can be positive or negative.

Formulas to find Volume of Plasma Cleared

Volume of Distribution

The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

Symbol: V_d

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Volume of Distribution

Other Formulas to find Elimination Rate Constant

Go Elimination Rate Constant given Area under Curve

k e = \frac{D}{AUC \cdot V d}

Go Elimination Rate Constant of Drug

k e = \frac{\ln (2)}{t b/2}

Other formulas in Elimination Rate Constant category

Go Elimination Half Life given Volume of Plasma Cleared

t b/2 = \frac{\ln (2) \cdot V d}{CL}

Go Elimination Half Life of Drug

t b/2 = \frac{\ln (2)}{k e}

Go Total Clearance of Body

CL total = CL hepatic + CL renal + CL pulmonary + CL other

How to Evaluate Elimination Rate Constant given Volume of Plasma Cleared?

Elimination Rate Constant given Volume of Plasma Cleared evaluator uses Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution to evaluate the Elimination Rate Constant, The Elimination rate constant given volume of plasma cleared formula is defined as the ratio of the volume of plasma cleared of the drug per unit time to the apparent volume in which a drug is distributed. Elimination Rate Constant is denoted by k_e symbol.

How to evaluate Elimination Rate Constant given Volume of Plasma Cleared using this online evaluator? To use this online evaluator for Elimination Rate Constant given Volume of Plasma Cleared, enter Volume of Plasma Cleared (CL) & Volume of Distribution (V_d) and hit the calculate button.

FAQs on Elimination Rate Constant given Volume of Plasma Cleared

What is the formula to find Elimination Rate Constant given Volume of Plasma Cleared?

The formula of Elimination Rate Constant given Volume of Plasma Cleared is expressed as Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution. Here is an example- 691200 = 0.00048/0.009.

How to calculate Elimination Rate Constant given Volume of Plasma Cleared?

With Volume of Plasma Cleared (CL) & Volume of Distribution (V_d) we can find Elimination Rate Constant given Volume of Plasma Cleared using the formula - Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution.

What are the other ways to Calculate Elimination Rate Constant?

Here are the different ways to Calculate Elimination Rate Constant-

Elimination Rate Constant=Dose/(Area Under Curve*Volume of Distribution)
Elimination Rate Constant=ln(2)/Elimination Half Life

Can the Elimination Rate Constant given Volume of Plasma Cleared be negative?

No, the Elimination Rate Constant given Volume of Plasma Cleared, measured in First Order Reaction Rate Constant cannot be negative.

Which unit is used to measure Elimination Rate Constant given Volume of Plasma Cleared?

Elimination Rate Constant given Volume of Plasma Cleared is usually measured using the 1 Per Hour[h⁻¹] for First Order Reaction Rate Constant. 1 Per Second[h⁻¹], 1 Per Millisecond[h⁻¹], 1 Per Day[h⁻¹] are the few other units in which Elimination Rate Constant given Volume of Plasma Cleared can be measured.

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