Dose of drug administered orally Formula

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The Dose Non-Intravenous is the amount of drug administered orally. Check FAQs
Dpo=AUCpoDivAUCivf
Dpo - Dose Non-Intravenous?AUCpo - Area under Curve Non-Intravenous?Div - Dose Intravenous?AUCiv - Area under Curve Intravenous?f - Bioavailability of Drug?

Dose of drug administered orally Example

With values
With units
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Here is how the Dose of drug administered orally equation looks like with Values.

Here is how the Dose of drug administered orally equation looks like with Units.

Here is how the Dose of drug administered orally equation looks like.

0.689Edit=6Edit12Edit11Edit9.5Edit
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Dose of drug administered orally Solution

Follow our step by step solution on how to calculate Dose of drug administered orally?

FIRST Step Consider the formula
Dpo=AUCpoDivAUCivf
Next Step Substitute values of Variables
Dpo=6mol*s/L12mol11mol*s/L9.5
Next Step Convert Units
Dpo=6000mol*s/m³12mol11000mol*s/m³9.5
Next Step Prepare to Evaluate
Dpo=600012110009.5
Next Step Evaluate
Dpo=0.688995215311005mol
LAST Step Rounding Answer
Dpo=0.689mol

Dose of drug administered orally Formula Elements

Variables
Dose Non-Intravenous
The Dose Non-Intravenous is the amount of drug administered orally.
Symbol: Dpo
Measurement: Amount of SubstanceUnit: mol
Note: Value should be greater than 0.
Area under Curve Non-Intravenous
The Area under Curve Non-Intravenous is the integral of the concentration-time curve after a single dose is administered orally.
Symbol: AUCpo
Measurement: Concentration Time CoefficientUnit: mol*s/L
Note: Value should be greater than 0.
Dose Intravenous
The Dose Intravenous is the amount of drug administered intravenously.
Symbol: Div
Measurement: Amount of SubstanceUnit: mol
Note: Value should be greater than 0.
Area under Curve Intravenous
Area under Curve Intravenous is the integral of the concentration-time curve after a single dose administered intravenous.
Symbol: AUCiv
Measurement: Concentration Time CoefficientUnit: mol*s/L
Note: Value can be positive or negative.
Bioavailability of Drug
The Bioavailability of Drug is defined as the systemically available fraction of a drug.
Symbol: f
Measurement: NAUnit: Unitless
Note: Value can be positive or negative.

Other formulas in Dose category

​Go Amount of drug administered given apparent volume
D=VdisCss
​Go Amount of drug in given volume of plasma
Css=DVdis
​Go Amount of drug administered given area under curve
D=CLAUC
​Go Dose given volume of distribution and area under curve
D=VdiskeAUC

How to Evaluate Dose of drug administered orally?

Dose of drug administered orally evaluator uses Dose Non-Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Bioavailability of Drug) to evaluate the Dose Non-Intravenous, The Dose of drug administered orally formula is defined as the comparison the bioavailability of the active drug in systemic circulation following non-intravenous administration to the bioavailability of the same drug following intravenous administration. Dose Non-Intravenous is denoted by Dpo symbol.

How to evaluate Dose of drug administered orally using this online evaluator? To use this online evaluator for Dose of drug administered orally, enter Area under Curve Non-Intravenous (AUCpo), Dose Intravenous (Div), Area under Curve Intravenous (AUCiv) & Bioavailability of Drug (f) and hit the calculate button.

FAQs on Dose of drug administered orally

What is the formula to find Dose of drug administered orally?
The formula of Dose of drug administered orally is expressed as Dose Non-Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Bioavailability of Drug). Here is an example- 0.688995 = (6000*12)/(11000*9.5).
How to calculate Dose of drug administered orally?
With Area under Curve Non-Intravenous (AUCpo), Dose Intravenous (Div), Area under Curve Intravenous (AUCiv) & Bioavailability of Drug (f) we can find Dose of drug administered orally using the formula - Dose Non-Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Bioavailability of Drug).
Can the Dose of drug administered orally be negative?
No, the Dose of drug administered orally, measured in Amount of Substance cannot be negative.
Which unit is used to measure Dose of drug administered orally?
Dose of drug administered orally is usually measured using the Mole[mol] for Amount of Substance. Millimole[mol], Kilomole[mol], Pound Mole[mol] are the few other units in which Dose of drug administered orally can be measured.
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