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Dose given volume of distribution and area under curve Formula

GoAmount of drug administered given apparent volume Formula

GoAmount of drug administered given area under curve Formula

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The Dose is the amount of drug administered. Check FAQs

D = V dis \cdot k e \cdot AUC

D - Dose?V_dis - Volume of Distribution?k_e - Elimination Rate Constant?AUC - Area Under Curve?

Dose given volume of distribution and area under curve Example

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Here is how the Dose given volume of distribution and area under curve equation looks like with Values.

Here is how the Dose given volume of distribution and area under curve equation looks like with Units.

Here is how the Dose given volume of distribution and area under curve equation looks like.

0.0002 = 9 \cdot 0.058 \cdot 1.32

0.0002mol = 9L \cdot 0.058h⁻¹ \cdot 1.32mol*s/L

0.0002 = 9 \cdot 0.058 \cdot 1.32

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Dose given volume of distribution and area under curve Solution

Follow our step by step solution on how to calculate Dose given volume of distribution and area under curve?

FIRST Step Consider the formula

D = V dis \cdot k e \cdot AUC

Next Step Substitute values of Variables

∴

D = 9L \cdot 0.058h⁻¹ \cdot 1.32mol*s/L

Next Step Convert Units

∴

D = 0.009m³ \cdot 1.6E-5s⁻¹ \cdot 1320mol*s/m³

Next Step Prepare to Evaluate

∴

D = 0.009 \cdot 1.6E-5 \cdot 1320

Next Step Evaluate

∴

D = 0.0001914mol

LAST Step Rounding Answer

∴

D = 0.0002mol

Dose given volume of distribution and area under curve Formula Elements

Variables

Dose

The Dose is the amount of drug administered.

Symbol: D

Measurement: Amount of SubstanceUnit: mol

Note: Value can be positive or negative.

Formulas to find Dose

Volume of Distribution

The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

Symbol: V_dis

Measurement: VolumeUnit: L

Note: Value can be positive or negative.

Formulas to find Volume of Distribution

Elimination Rate Constant

Elimination Rate Constant is the rate at which a drug is removed from the body.

Symbol: k_e

Measurement: First Order Reaction Rate ConstantUnit: h⁻¹

Note: Value should be greater than 0.

Formulas to find Elimination Rate Constant

Area Under Curve

Area under Curve (AUC) is the definite integral of a curve that describes the variation of a drug concentration in blood plasma as a function of time.

Symbol: AUC

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value can be positive or negative.

Formulas to find Area Under Curve

Other Formulas to find Dose

Go Amount of drug administered given apparent volume

D = V dis \cdot C ss

Go Amount of drug administered given area under curve

D = CL \cdot AUC

Other formulas in Dose category

Go Amount of drug in given volume of plasma

C ss = \frac{D}{V dis}

Go Dose of drug administered intravenous

D iv = \frac{f \cdot AUC iv \cdot D po}{AUC po}

Go Dose of drug administered orally

D po = \frac{AUC po \cdot D iv}{AUC iv \cdot f}

Go Dose of A type drug

D A = (\frac{AUC dosageA}{AUC dosageB}) \cdot (\frac{D B}{F rel})

How to Evaluate Dose given volume of distribution and area under curve?

Dose given volume of distribution and area under curve evaluator uses Dose = Volume of Distribution*Elimination Rate Constant*Area Under Curve to evaluate the Dose, Dose given volume of distribution and area under curve formula is defined as the product of the apparent volume in which a drug is distributed with rate at which a drug is removed from the body and area under the curve of concentration-time graph. Dose is denoted by D symbol.

How to evaluate Dose given volume of distribution and area under curve using this online evaluator? To use this online evaluator for Dose given volume of distribution and area under curve, enter Volume of Distribution (V_dis), Elimination Rate Constant (k_e) & Area Under Curve (AUC) and hit the calculate button.

FAQs on Dose given volume of distribution and area under curve

What is the formula to find Dose given volume of distribution and area under curve?

The formula of Dose given volume of distribution and area under curve is expressed as Dose = Volume of Distribution*Elimination Rate Constant*Area Under Curve. Here is an example- 0.000191 = 0.009*1.61111111111111E-05*1320.

How to calculate Dose given volume of distribution and area under curve?

With Volume of Distribution (V_dis), Elimination Rate Constant (k_e) & Area Under Curve (AUC) we can find Dose given volume of distribution and area under curve using the formula - Dose = Volume of Distribution*Elimination Rate Constant*Area Under Curve.

What are the other ways to Calculate Dose?

Here are the different ways to Calculate Dose-

Dose=Volume of Distribution*Concentration of Drug
Dose=Volume of Plasma Cleared*Area Under Curve

Can the Dose given volume of distribution and area under curve be negative?

Yes, the Dose given volume of distribution and area under curve, measured in Amount of Substance can be negative.

Which unit is used to measure Dose given volume of distribution and area under curve?

Dose given volume of distribution and area under curve is usually measured using the Mole[mol] for Amount of Substance. Millimole[mol], Kilomole[mol], Pound Mole[mol] are the few other units in which Dose given volume of distribution and area under curve can be measured.

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Dose given volume of distribution and area under curve Formula

​GoAmount of drug administered given apparent volume Formula

​GoAmount of drug administered given area under curve Formula

Dose given volume of distribution and area under curve Example

Dose given volume of distribution and area under curve Solution

Dose given volume of distribution and area under curve Formula Elements

Other Formulas to find Dose

Other formulas in Dose category

How to Evaluate Dose given volume of distribution and area under curve?

FAQs on Dose given volume of distribution and area under curve

Variable Name

GoAmount of drug administered given apparent volume Formula

GoAmount of drug administered given area under curve Formula