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The Dissociation Rate Constant is the ratio of reverse and forward rate constant. Check FAQs
KD=(VmaxSV0)-S
KD - Dissociation Rate Constant?Vmax - Maximum Rate?S - Substrate Concentration?V0 - Initial Reaction Rate?

Dissociation Rate Constant given Concentration of Enzyme and Substrate Example

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Here is how the Dissociation Rate Constant given Concentration of Enzyme and Substrate equation looks like with Values.

Here is how the Dissociation Rate Constant given Concentration of Enzyme and Substrate equation looks like with Units.

Here is how the Dissociation Rate Constant given Concentration of Enzyme and Substrate equation looks like.

131.8333Edit=(40Edit1.5Edit0.45Edit)-1.5Edit
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Dissociation Rate Constant given Concentration of Enzyme and Substrate Solution

Follow our step by step solution on how to calculate Dissociation Rate Constant given Concentration of Enzyme and Substrate?

FIRST Step Consider the formula
KD=(VmaxSV0)-S
Next Step Substitute values of Variables
KD=(40mol/L*s1.5mol/L0.45mol/L*s)-1.5mol/L
Next Step Convert Units
KD=(40000mol/m³*s1500mol/m³450mol/m³*s)-1500mol/m³
Next Step Prepare to Evaluate
KD=(400001500450)-1500
Next Step Evaluate
KD=131833.333333333mol/m³
Next Step Convert to Output's Unit
KD=131.833333333333mol/L
LAST Step Rounding Answer
KD=131.8333mol/L

Dissociation Rate Constant given Concentration of Enzyme and Substrate Formula Elements

Variables
Dissociation Rate Constant
The Dissociation Rate Constant is the ratio of reverse and forward rate constant.
Symbol: KD
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Maximum Rate
The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Symbol: Vmax
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Substrate Concentration
The Substrate Concentration is the number of moles of substrate per liter solution.
Symbol: S
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Initial Reaction Rate
The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Symbol: V0
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.

Other Formulas to find Dissociation Rate Constant

​Go Dissociation Rate Constant in Enzymatic Reaction Mechanism
KD=krkf
​Go Dissociation Rate Constant given Catalytic Rate Constant
KD=(kcat[E0]SV0)-S

Other formulas in Rate Constants of Enzymatic Reaction category

​Go Catalytic Rate Constant at Low Substrate Concentration
kcat=V0KM[E0]S
​Go Forward Rate Constant in Enzymatic Reaction mechanism
kf=krESS([E0]-ES)
​Go Reverse Rate Constant in Enzymatic Reaction Mechanism
kr=kfS([E0]-ES)ES
​Go Forward Rate Constant given Dissociation Rate Constant
kf=(krKD)

How to Evaluate Dissociation Rate Constant given Concentration of Enzyme and Substrate?

Dissociation Rate Constant given Concentration of Enzyme and Substrate evaluator uses Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration to evaluate the Dissociation Rate Constant, The Dissociation rate constant given concentration of enzyme and substrate formula is defined as the relation with the maximum rate achieved by the system, initial rate of the system, and with substrate concentration. Dissociation Rate Constant is denoted by KD symbol.

How to evaluate Dissociation Rate Constant given Concentration of Enzyme and Substrate using this online evaluator? To use this online evaluator for Dissociation Rate Constant given Concentration of Enzyme and Substrate, enter Maximum Rate (Vmax), Substrate Concentration (S) & Initial Reaction Rate (V0) and hit the calculate button.

FAQs on Dissociation Rate Constant given Concentration of Enzyme and Substrate

What is the formula to find Dissociation Rate Constant given Concentration of Enzyme and Substrate?
The formula of Dissociation Rate Constant given Concentration of Enzyme and Substrate is expressed as Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration. Here is an example- 0.131833 = ((40000*1500)/450)-1500.
How to calculate Dissociation Rate Constant given Concentration of Enzyme and Substrate?
With Maximum Rate (Vmax), Substrate Concentration (S) & Initial Reaction Rate (V0) we can find Dissociation Rate Constant given Concentration of Enzyme and Substrate using the formula - Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration.
What are the other ways to Calculate Dissociation Rate Constant?
Here are the different ways to Calculate Dissociation Rate Constant-
  • Dissociation Rate Constant=Reverse Rate Constant/Forward Rate ConstantOpenImg
  • Dissociation Rate Constant=((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate ConcentrationOpenImg
Can the Dissociation Rate Constant given Concentration of Enzyme and Substrate be negative?
Yes, the Dissociation Rate Constant given Concentration of Enzyme and Substrate, measured in Molar Concentration can be negative.
Which unit is used to measure Dissociation Rate Constant given Concentration of Enzyme and Substrate?
Dissociation Rate Constant given Concentration of Enzyme and Substrate is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Dissociation Rate Constant given Concentration of Enzyme and Substrate can be measured.
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