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Degradation Rate Constant Formula

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The Degradation Rate Constant is a parameter that describes the rate at which a drug undergoes degradation or breaks down over time. Check FAQs

K o = A o - \frac{A t}{t}

K_o - Degradation Rate Constant?A_o - Initial Concentration Drug?A_t - Concentration After Some Time?t - Time Rate Drug?

Degradation Rate Constant Example

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With units

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Here is how the Degradation Rate Constant equation looks like with Values.

Here is how the Degradation Rate Constant equation looks like with Units.

Here is how the Degradation Rate Constant equation looks like.

2.3E-6 = 200 - \frac{125}{8}

2.3E-6d = 200mg/L - \frac{125mg/L}{8h}

2.3E-6 = 200 - \frac{125}{8}

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Degradation Rate Constant Solution

Follow our step by step solution on how to calculate Degradation Rate Constant?

FIRST Step Consider the formula

K o = A o - \frac{A t}{t}

Next Step Substitute values of Variables

∴

K o = 200mg/L - \frac{125mg/L}{8h}

Next Step Convert Units

∴

K o = 0.2kg/m³ - \frac{0.125kg/m³}{28800s}

Next Step Prepare to Evaluate

∴

K o = 0.2 - \frac{0.125}{28800}

Next Step Evaluate

∴

K o = 0.199995659722222s

Next Step Convert to Output's Unit

∴

K o = 2.31476458011831E-06d

LAST Step Rounding Answer

∴

K o = 2.3E-6d

Degradation Rate Constant Formula Elements

Variables

Degradation Rate Constant

The Degradation Rate Constant is a parameter that describes the rate at which a drug undergoes degradation or breaks down over time.

Symbol: K_o

Measurement: TimeUnit: d

Note: Value should be greater than 0.

Formulas to find Degradation Rate Constant

Initial Concentration Drug

The Initial Concentration Drug is the drug at the start of the degradation process, usually at time zero. It provides the baseline concentration from which the degradation is measured.

Symbol: A_o

Measurement: Mass ConcentrationUnit: mg/L

Note: Value should be greater than 0.

Formulas to find Initial Concentration Drug

Concentration After Some Time

The Concentration After Some Time is the concentration of the drug after a specified amount of time (t) has passed.

Symbol: A_t

Measurement: Mass ConcentrationUnit: mg/L

Note: Value should be greater than 0.

Formulas to find Concentration After Some Time

Time Rate Drug

The Time Rate drug for degradation is the duration for which the drug has been degrading.

Symbol: t

Measurement: TimeUnit: h

Note: Value should be greater than 0.

Formulas to find Time Rate Drug

Other formulas in Drug Stability category

Go Acceleration Factor

AF = \frac{T f}{T t}

Go Shelf Life for Zero Order

T 10% = \frac{A o}{10} \cdot K o

Go Shelf Life for First Order

T 10% = \frac{0.105}{A o}

How to Evaluate Degradation Rate Constant?

Degradation Rate Constant evaluator uses Degradation Rate Constant = Initial Concentration Drug-Concentration After Some Time/Time Rate Drug to evaluate the Degradation Rate Constant, The Degradation Rate Constant formula is defined as the parameter that describes the rate at which a drug undergoes degradation or breaks down over time. It is a constant value specific to the drug and the conditions under which it is stored. The units of the degradation rate constant depend on the order of the reaction and the units of concentration used. Degradation Rate Constant is denoted by K_o symbol.

How to evaluate Degradation Rate Constant using this online evaluator? To use this online evaluator for Degradation Rate Constant, enter Initial Concentration Drug (A_o), Concentration After Some Time (A_t) & Time Rate Drug (t) and hit the calculate button.

FAQs on Degradation Rate Constant

What is the formula to find Degradation Rate Constant?

The formula of Degradation Rate Constant is expressed as Degradation Rate Constant = Initial Concentration Drug-Concentration After Some Time/Time Rate Drug. Here is an example- 2.7E-11 = 0.2-0.125/28800.

How to calculate Degradation Rate Constant?

With Initial Concentration Drug (A_o), Concentration After Some Time (A_t) & Time Rate Drug (t) we can find Degradation Rate Constant using the formula - Degradation Rate Constant = Initial Concentration Drug-Concentration After Some Time/Time Rate Drug.

Can the Degradation Rate Constant be negative?

No, the Degradation Rate Constant, measured in Time cannot be negative.

Which unit is used to measure Degradation Rate Constant?

Degradation Rate Constant is usually measured using the Day[d] for Time. Second[d], Millisecond[d], Microsecond[d] are the few other units in which Degradation Rate Constant can be measured.

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Degradation Rate Constant Formula

Degradation Rate Constant Example

Degradation Rate Constant Solution

Degradation Rate Constant Formula Elements

Other formulas in Drug Stability category

How to Evaluate Degradation Rate Constant?

FAQs on Degradation Rate Constant

Variable Name