FormulaDen.com

Physics Chemistry Math Chemical Engineering Civil Electrical Electronics Electronics and Instrumentation Materials Science Mechanical Production Engineering Financial Health

Clearance for Desired Steady State Concentration Formula

Fx Copy

LaTeX Copy

The Clearance drug can be defined as the amount of rate at which a drug is removed from the body, and it can be calculated using the product of Vd and K. Check FAQs

C d = F \cdot \frac{D ss}{C ss} \cdot τ

C_d - Clearance Drug?F - Bioavailability Steady State?D_ss - Dose Cal Steady State?C_ss - Steady State Concentration of Drug?τ - Dosing Interval Steady State?

Clearance for Desired Steady State Concentration Example

With values

With units

Only example

Here is how the Clearance for Desired Steady State Concentration equation looks like with Values.

Here is how the Clearance for Desired Steady State Concentration equation looks like with Units.

Here is how the Clearance for Desired Steady State Concentration equation looks like.

3.5E+10 = 0.8 \cdot \frac{250}{10} \cdot 8

3.5E+10mL/min = 0.8 \cdot \frac{250mg}{10mg/L} \cdot 8h

3.5E+10 = 0.8 \cdot \frac{250}{10} \cdot 8

Tip: Use pencil ( Pencil

) icon above to edit Input Values and Units.

Calculate

Recalculate

Solution

Copy

Reset

You are here -

Home » Category

Chemistry » Category

Pharmacokinetics » Category

Steady state Concentration » fx Clearance for Desired Steady State Concentration

Clearance for Desired Steady State Concentration Solution

Follow our step by step solution on how to calculate Clearance for Desired Steady State Concentration?

FIRST Step Consider the formula

C d = F \cdot \frac{D ss}{C ss} \cdot τ

Next Step Substitute values of Variables

∴

C d = 0.8 \cdot \frac{250mg}{10mg/L} \cdot 8h

Next Step Convert Units

∴

C d = 0.8 \cdot \frac{0.0002kg}{0.01kg/m³} \cdot 28800s

Next Step Prepare to Evaluate

∴

C d = 0.8 \cdot \frac{0.0002}{0.01} \cdot 28800

Next Step Evaluate

∴

C d = 576m³/s

Next Step Convert to Output's Unit

∴

C d = 34560000000mL/min

LAST Step Rounding Answer

∴

C d = 3.5E+10mL/min

Clearance for Desired Steady State Concentration Formula Elements

Variables

Clearance Drug

The Clearance drug can be defined as the amount of rate at which a drug is removed from the body, and it can be calculated using the product of Vd and K.

Symbol: C_d

Measurement: Volumetric Flow RateUnit: mL/min

Note: Value should be greater than 0.

Formulas to find Clearance Drug

Bioavailability Steady State

The Bioavailability Steady State refers to the proportion of an administered dose of a drug or substance that enters the bloodstream and becomes available to exert its therapeutic effect.

Symbol: F

Measurement: NAUnit: Unitless

Note: Value should be greater than 0.

Formulas to find Bioavailability Steady State

Dose Cal Steady State

The Dose Cal Steady State represents the amount of the drug that needs to be administered to achieve the desired steady-state concentration (Css).

Symbol: D_ss

Measurement: WeightUnit: mg

Note: Value should be greater than 0.

Formulas to find Dose Cal Steady State

Steady State Concentration of Drug

The Steady State Concentration of Drug stands for the desired steady-state concentration of the drug in the body. It represents the target concentration you want to achieve for the drug.

Symbol: C_ss

Measurement: Mass ConcentrationUnit: mg/L

Note: Value should be greater than 0.

Formulas to find Steady State Concentration of Drug

Dosing Interval Steady State

The Dosing Interval Steady State represents the time interval between successive doses of the drug. It is the time it takes for one complete dosing cycle.

Symbol: τ

Measurement: TimeUnit: h

Note: Value should be greater than 0.

Formulas to find Dosing Interval Steady State

Other formulas in Steady state Concentration category

Go Dose Calculation for Desired Steady State Concentration

D ss = C ss \cdot C d \cdot τ

Go Bioavailability Calculation for Desired Steady State Concentration

F = C ss \cdot D ss \cdot \frac{τ}{C d}

Go Dosing Interval Adjustment for Desired Steady State Concentration

τ = F \cdot \frac{D ss}{C ss} \cdot C d

Go Dose Calculation for Desired Steady State Concentration and Bioavailability

D ss = C ss \cdot C d \cdot \frac{τ}{F}

How to Evaluate Clearance for Desired Steady State Concentration?

Clearance for Desired Steady State Concentration evaluator uses Clearance Drug = Bioavailability Steady State*Dose Cal Steady State/Steady State Concentration of Drug*Dosing Interval Steady State to evaluate the Clearance Drug, The Clearance for desired steady state concentration formula is defined as the rate at which the drug is eliminated from the body. It represents the volume of plasma from which the drug is completely removed per unit of time. Clearance is usually expressed in units like liters per hour (L/h) or milliliters per minute (mL/min). Clearance Drug is denoted by C_d symbol.

How to evaluate Clearance for Desired Steady State Concentration using this online evaluator? To use this online evaluator for Clearance for Desired Steady State Concentration, enter Bioavailability Steady State (F), Dose Cal Steady State (D_ss), Steady State Concentration of Drug (C_ss) & Dosing Interval Steady State (τ) and hit the calculate button.

FAQs on Clearance for Desired Steady State Concentration

What is the formula to find Clearance for Desired Steady State Concentration?

The formula of Clearance for Desired Steady State Concentration is expressed as Clearance Drug = Bioavailability Steady State*Dose Cal Steady State/Steady State Concentration of Drug*Dosing Interval Steady State. Here is an example- 2.1E+18 = 0.8*0.00025/0.01*28800.

How to calculate Clearance for Desired Steady State Concentration?

With Bioavailability Steady State (F), Dose Cal Steady State (D_ss), Steady State Concentration of Drug (C_ss) & Dosing Interval Steady State (τ) we can find Clearance for Desired Steady State Concentration using the formula - Clearance Drug = Bioavailability Steady State*Dose Cal Steady State/Steady State Concentration of Drug*Dosing Interval Steady State.

Can the Clearance for Desired Steady State Concentration be negative?

No, the Clearance for Desired Steady State Concentration, measured in Volumetric Flow Rate cannot be negative.

Which unit is used to measure Clearance for Desired Steady State Concentration?

Clearance for Desired Steady State Concentration is usually measured using the Milliliter per Minute[mL/min] for Volumetric Flow Rate. Cubic Meter per Second[mL/min], Cubic Meter per Day[mL/min], Cubic Meter per Hour[mL/min] are the few other units in which Clearance for Desired Steady State Concentration can be measured.

Let Others Know

✖

Facebook

Twitter

Copied!

Clearance for Desired Steady State Concentration Formula

Clearance for Desired Steady State Concentration Example

Clearance for Desired Steady State Concentration Solution

Clearance for Desired Steady State Concentration Formula Elements

Other formulas in Steady state Concentration category

How to Evaluate Clearance for Desired Steady State Concentration?

FAQs on Clearance for Desired Steady State Concentration

Variable Name