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The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product. Check FAQs
kcat=(kfESES)-kr
kcat - Catalytic Rate Constant?kf - Forward Rate Constant?E - Catalyst Concentration?S - Substrate Concentration?ES - Enzyme Substrate Complex Concentration?kr - Reverse Rate Constant?

Catalytic Rate Constant given Reverse and Forward Rate Constant Example

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With units
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Here is how the Catalytic Rate Constant given Reverse and Forward Rate Constant equation looks like with Values.

Here is how the Catalytic Rate Constant given Reverse and Forward Rate Constant equation looks like with Units.

Here is how the Catalytic Rate Constant given Reverse and Forward Rate Constant equation looks like.

5875Edit=(6.9Edit25Edit1.5Edit10Edit)-20Edit
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Catalytic Rate Constant given Reverse and Forward Rate Constant Solution

Follow our step by step solution on how to calculate Catalytic Rate Constant given Reverse and Forward Rate Constant?

FIRST Step Consider the formula
kcat=(kfESES)-kr
Next Step Substitute values of Variables
kcat=(6.9s⁻¹25mol/L1.5mol/L10mol/L)-20mol/L*s
Next Step Convert Units
kcat=(6.9s⁻¹25000mol/m³1500mol/m³10000mol/m³)-20000mol/m³*s
Next Step Prepare to Evaluate
kcat=(6.925000150010000)-20000
LAST Step Evaluate
kcat=5875s⁻¹

Catalytic Rate Constant given Reverse and Forward Rate Constant Formula Elements

Variables
Catalytic Rate Constant
The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.
Symbol: kcat
Measurement: First Order Reaction Rate ConstantUnit: s⁻¹
Note: Value can be positive or negative.
Forward Rate Constant
The Forward Rate Constant is defined as the rate constant for the forward occurring reaction.
Symbol: kf
Measurement: First Order Reaction Rate ConstantUnit: s⁻¹
Note: Value can be positive or negative.
Catalyst Concentration
The Catalyst Concentration is the number of moles of catalyst present in the per liter of solution.
Symbol: E
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Substrate Concentration
The Substrate Concentration is the number of moles of substrate per liter solution.
Symbol: S
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Enzyme Substrate Complex Concentration
The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.
Symbol: ES
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Reverse Rate Constant
The Reverse Rate Constant is defined as the rate constant for the backward reaction.
Symbol: kr
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.

Other Formulas to find Catalytic Rate Constant

​Go Catalytic Rate Constant at Low Substrate Concentration
kcat=V0KM[E0]S
​Go Catalytic Rate Constant given Dissociation Rate Constant
kcat=V0(KD+S)[E0]S

Other formulas in Rate Constants of Enzymatic Reaction category

​Go Forward Rate Constant in Enzymatic Reaction mechanism
kf=krESS([E0]-ES)
​Go Reverse Rate Constant in Enzymatic Reaction Mechanism
kr=kfS([E0]-ES)ES
​Go Dissociation Rate Constant in Enzymatic Reaction Mechanism
KD=krkf
​Go Forward Rate Constant given Dissociation Rate Constant
kf=(krKD)

How to Evaluate Catalytic Rate Constant given Reverse and Forward Rate Constant?

Catalytic Rate Constant given Reverse and Forward Rate Constant evaluator uses Catalytic Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Reverse Rate Constant to evaluate the Catalytic Rate Constant, The Catalytic rate constant given reverse and forward rate constant formula is defined as the relation with enzymatic catalyst and substrate concentration with an enzyme-substrate complex concentration in an enzymatic reaction mechanism. Catalytic Rate Constant is denoted by kcat symbol.

How to evaluate Catalytic Rate Constant given Reverse and Forward Rate Constant using this online evaluator? To use this online evaluator for Catalytic Rate Constant given Reverse and Forward Rate Constant, enter Forward Rate Constant (kf), Catalyst Concentration (E), Substrate Concentration (S), Enzyme Substrate Complex Concentration (ES) & Reverse Rate Constant (kr) and hit the calculate button.

FAQs on Catalytic Rate Constant given Reverse and Forward Rate Constant

What is the formula to find Catalytic Rate Constant given Reverse and Forward Rate Constant?
The formula of Catalytic Rate Constant given Reverse and Forward Rate Constant is expressed as Catalytic Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Reverse Rate Constant. Here is an example- 5875 = ((6.9*25000*1500)/10000)-20000.
How to calculate Catalytic Rate Constant given Reverse and Forward Rate Constant?
With Forward Rate Constant (kf), Catalyst Concentration (E), Substrate Concentration (S), Enzyme Substrate Complex Concentration (ES) & Reverse Rate Constant (kr) we can find Catalytic Rate Constant given Reverse and Forward Rate Constant using the formula - Catalytic Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Reverse Rate Constant.
What are the other ways to Calculate Catalytic Rate Constant?
Here are the different ways to Calculate Catalytic Rate Constant-
  • Catalytic Rate Constant=(Initial Reaction Rate*Michaelis Constant)/(Initial Enzyme Concentration*Substrate Concentration)OpenImg
  • Catalytic Rate Constant=(Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)OpenImg
Can the Catalytic Rate Constant given Reverse and Forward Rate Constant be negative?
Yes, the Catalytic Rate Constant given Reverse and Forward Rate Constant, measured in First Order Reaction Rate Constant can be negative.
Which unit is used to measure Catalytic Rate Constant given Reverse and Forward Rate Constant?
Catalytic Rate Constant given Reverse and Forward Rate Constant is usually measured using the 1 Per Second[s⁻¹] for First Order Reaction Rate Constant. 1 Per Millisecond[s⁻¹], 1 Per Day[s⁻¹], 1 Per Hour[s⁻¹] are the few other units in which Catalytic Rate Constant given Reverse and Forward Rate Constant can be measured.
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