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The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product. Check FAQs
kcat=V0(KD+S)[E0]S
kcat - Catalytic Rate Constant?V0 - Initial Reaction Rate?KD - Dissociation Rate Constant?S - Substrate Concentration?[E0] - Initial Enzyme Concentration?

Catalytic Rate Constant given Dissociation Rate Constant Example

With values
With units
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Here is how the Catalytic Rate Constant given Dissociation Rate Constant equation looks like with Values.

Here is how the Catalytic Rate Constant given Dissociation Rate Constant equation looks like with Units.

Here is how the Catalytic Rate Constant given Dissociation Rate Constant equation looks like.

0.0216Edit=0.45Edit(5.7Edit+1.5Edit)100Edit1.5Edit
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Catalytic Rate Constant given Dissociation Rate Constant Solution

Follow our step by step solution on how to calculate Catalytic Rate Constant given Dissociation Rate Constant?

FIRST Step Consider the formula
kcat=V0(KD+S)[E0]S
Next Step Substitute values of Variables
kcat=0.45mol/L*s(5.7mol/L+1.5mol/L)100mol/L1.5mol/L
Next Step Convert Units
kcat=450mol/m³*s(5700mol/m³+1500mol/m³)100000mol/m³1500mol/m³
Next Step Prepare to Evaluate
kcat=450(5700+1500)1000001500
LAST Step Evaluate
kcat=0.0216s⁻¹

Catalytic Rate Constant given Dissociation Rate Constant Formula Elements

Variables
Catalytic Rate Constant
The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.
Symbol: kcat
Measurement: First Order Reaction Rate ConstantUnit: s⁻¹
Note: Value can be positive or negative.
Initial Reaction Rate
The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Symbol: V0
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Dissociation Rate Constant
The Dissociation Rate Constant is the ratio of reverse and forward rate constant.
Symbol: KD
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Substrate Concentration
The Substrate Concentration is the number of moles of substrate per liter solution.
Symbol: S
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Initial Enzyme Concentration
The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.
Symbol: [E0]
Measurement: Molar ConcentrationUnit: mol/L
Note: Value should be greater than 0.

Other Formulas to find Catalytic Rate Constant

​Go Catalytic Rate Constant at Low Substrate Concentration
kcat=V0KM[E0]S
​Go Catalytic Rate Constant given Reverse and Forward Rate Constant
kcat=(kfESES)-kr

Other formulas in Rate Constants of Enzymatic Reaction category

​Go Forward Rate Constant in Enzymatic Reaction mechanism
kf=krESS([E0]-ES)
​Go Reverse Rate Constant in Enzymatic Reaction Mechanism
kr=kfS([E0]-ES)ES
​Go Dissociation Rate Constant in Enzymatic Reaction Mechanism
KD=krkf
​Go Forward Rate Constant given Dissociation Rate Constant
kf=(krKD)

How to Evaluate Catalytic Rate Constant given Dissociation Rate Constant?

Catalytic Rate Constant given Dissociation Rate Constant evaluator uses Catalytic Rate Constant = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration) to evaluate the Catalytic Rate Constant, The Catalytic rate constant given dissociation rate constant formula is defined as the relation with initial and dissociation rate constants of the system and with the enzyme and substrate concentration. Catalytic Rate Constant is denoted by kcat symbol.

How to evaluate Catalytic Rate Constant given Dissociation Rate Constant using this online evaluator? To use this online evaluator for Catalytic Rate Constant given Dissociation Rate Constant, enter Initial Reaction Rate (V0), Dissociation Rate Constant (KD), Substrate Concentration (S) & Initial Enzyme Concentration ([E0]) and hit the calculate button.

FAQs on Catalytic Rate Constant given Dissociation Rate Constant

What is the formula to find Catalytic Rate Constant given Dissociation Rate Constant?
The formula of Catalytic Rate Constant given Dissociation Rate Constant is expressed as Catalytic Rate Constant = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration). Here is an example- 0.0216 = (450*(5700+1500))/(100000*1500).
How to calculate Catalytic Rate Constant given Dissociation Rate Constant?
With Initial Reaction Rate (V0), Dissociation Rate Constant (KD), Substrate Concentration (S) & Initial Enzyme Concentration ([E0]) we can find Catalytic Rate Constant given Dissociation Rate Constant using the formula - Catalytic Rate Constant = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration).
What are the other ways to Calculate Catalytic Rate Constant?
Here are the different ways to Calculate Catalytic Rate Constant-
  • Catalytic Rate Constant=(Initial Reaction Rate*Michaelis Constant)/(Initial Enzyme Concentration*Substrate Concentration)OpenImg
  • Catalytic Rate Constant=((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Reverse Rate ConstantOpenImg
Can the Catalytic Rate Constant given Dissociation Rate Constant be negative?
Yes, the Catalytic Rate Constant given Dissociation Rate Constant, measured in First Order Reaction Rate Constant can be negative.
Which unit is used to measure Catalytic Rate Constant given Dissociation Rate Constant?
Catalytic Rate Constant given Dissociation Rate Constant is usually measured using the 1 Per Second[s⁻¹] for First Order Reaction Rate Constant. 1 Per Millisecond[s⁻¹], 1 Per Day[s⁻¹], 1 Per Hour[s⁻¹] are the few other units in which Catalytic Rate Constant given Dissociation Rate Constant can be measured.
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