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Bioavailability of Drug given Maintenance Dose Formula

GoBioavailability of Drug Dose given Loading Dose Formula

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The Bioavailability Of drug dose is describe the fraction or percentage of administration drug that reaches the systemic circulation in an unchanged and active form. Check FAQs

F% = \frac{CL drug \cdot C p}{MD}

F% - Bioavailability Of drug dose?CL_drug - Drug Clearance?C_p - Target Plasma Concentration?MD - Maintenance Dose?

Bioavailability of Drug given Maintenance Dose Example

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Here is how the Bioavailability of Drug given Maintenance Dose equation looks like with Values.

Here is how the Bioavailability of Drug given Maintenance Dose equation looks like with Units.

Here is how the Bioavailability of Drug given Maintenance Dose equation looks like.

3.1E+6 = \frac{2 \cdot 30}{70}

3.1E+6 = \frac{2m³/s \cdot 30mg/L}{70mg/h}

3.1E+6 = \frac{2 \cdot 30}{70}

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Bioavailability of Drug given Maintenance Dose Solution

Follow our step by step solution on how to calculate Bioavailability of Drug given Maintenance Dose?

FIRST Step Consider the formula

F% = \frac{CL drug \cdot C p}{MD}

Next Step Substitute values of Variables

∴

F% = \frac{2m³/s \cdot 30mg/L}{70mg/h}

Next Step Convert Units

∴

F% = \frac{2m³/s \cdot 0.03kg/m³}{1.9E-8kg/s}

Next Step Prepare to Evaluate

∴

F% = \frac{2 \cdot 0.03}{1.9E-8}

Next Step Evaluate

∴

F% = 3085714.28571429

LAST Step Rounding Answer

∴

F% = 3.1E+6

Bioavailability of Drug given Maintenance Dose Formula Elements

Variables

Bioavailability Of drug dose

The Bioavailability Of drug dose is describe the fraction or percentage of administration drug that reaches the systemic circulation in an unchanged and active form.

Symbol: F%

Measurement: NAUnit: Unitless

Note: Value can be positive or negative.

Formulas to find Bioavailability Of drug dose

Drug Clearance

Drug Clearance is the rate at which a drug or its metabolites are removed from the body and systemic circulation.

Symbol: CL_drug

Measurement: Volumetric Flow RateUnit: m³/s

Note: Value can be positive or negative.

Formulas to find Drug Clearance

Target Plasma Concentration

The Target Plasma Concentration is refer to the desired or optimal concentration of a drug in the bloodstream at a specific time after the administration.

Symbol: C_p

Measurement: Mass ConcentrationUnit: mg/L

Note: Value should be greater than 0.

Formulas to find Target Plasma Concentration

Maintenance Dose

The Maintenance Dose is the dose of a drug that is administered on a regular basis to maintained a desired plasma concentration.

Symbol: MD

Measurement: Mass Flow RateUnit: mg/h

Note: Value should be greater than 0.

Formulas to find Maintenance Dose

Other Formulas to find Bioavailability Of drug dose

Go Bioavailability of Drug Dose given Loading Dose

F% = \frac{V d \cdot C p}{LD}

Other formulas in Dose category

Go Amount of drug administered given apparent volume

D = V dis \cdot C ss

Go Amount of drug in given volume of plasma

C ss = \frac{D}{V dis}

Go Amount of drug administered given area under curve

D = CL \cdot AUC

Go Dose given volume of distribution and area under curve

D = V dis \cdot k e \cdot AUC

How to Evaluate Bioavailability of Drug given Maintenance Dose?

Bioavailability of Drug given Maintenance Dose evaluator uses Bioavailability Of drug dose = (Drug Clearance*Target Plasma Concentration)/Maintenance Dose to evaluate the Bioavailability Of drug dose, The Bioavailability of Drug given Maintenance Dose formula is defined as the ratio of the product of the clearance of drug and target plasma concentration to the maintenance dose. Bioavailability Of drug dose is denoted by F% symbol.

How to evaluate Bioavailability of Drug given Maintenance Dose using this online evaluator? To use this online evaluator for Bioavailability of Drug given Maintenance Dose, enter Drug Clearance (CL_drug), Target Plasma Concentration (C_p) & Maintenance Dose (MD) and hit the calculate button.

FAQs on Bioavailability of Drug given Maintenance Dose

What is the formula to find Bioavailability of Drug given Maintenance Dose?

The formula of Bioavailability of Drug given Maintenance Dose is expressed as Bioavailability Of drug dose = (Drug Clearance*Target Plasma Concentration)/Maintenance Dose. Here is an example- 3.1E+6 = (2*0.03)/1.94444444444444E-08.

How to calculate Bioavailability of Drug given Maintenance Dose?

With Drug Clearance (CL_drug), Target Plasma Concentration (C_p) & Maintenance Dose (MD) we can find Bioavailability of Drug given Maintenance Dose using the formula - Bioavailability Of drug dose = (Drug Clearance*Target Plasma Concentration)/Maintenance Dose.

What are the other ways to Calculate Bioavailability Of drug dose?

Here are the different ways to Calculate Bioavailability Of drug dose-

Bioavailability Of drug dose=(Volume Of Distribution dose*Target Plasma Concentration)/Loading Dose

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