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Bioavailability of Drug Formula

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The Bioavailability of Drug is defined as the systemically available fraction of a drug. Check FAQs

f = \frac{AUC po \cdot D iv}{AUC iv \cdot D po}

f - Bioavailability of Drug?AUC_po - Area under Curve Non-Intravenous?D_iv - Dose Intravenous?AUC_iv - Area under Curve Intravenous?D_po - Dose Non-Intravenous?

Bioavailability of Drug Example

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Here is how the Bioavailability of Drug equation looks like with Values.

Here is how the Bioavailability of Drug equation looks like with Units.

Here is how the Bioavailability of Drug equation looks like.

1.6364 = \frac{6 \cdot 12}{11 \cdot 4}

1.6364 = \frac{6mol*s/L \cdot 12mol}{11mol*s/L \cdot 4mol}

1.6364 = \frac{6 \cdot 12}{11 \cdot 4}

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Bioavailability of Drug Solution

Follow our step by step solution on how to calculate Bioavailability of Drug?

FIRST Step Consider the formula

f = \frac{AUC po \cdot D iv}{AUC iv \cdot D po}

Next Step Substitute values of Variables

∴

f = \frac{6mol*s/L \cdot 12mol}{11mol*s/L \cdot 4mol}

Next Step Convert Units

∴

f = \frac{6000mol*s/m³ \cdot 12mol}{11000mol*s/m³ \cdot 4mol}

Next Step Prepare to Evaluate

∴

f = \frac{6000 \cdot 12}{11000 \cdot 4}

Next Step Evaluate

∴

f = 1.63636363636364

LAST Step Rounding Answer

∴

f = 1.6364

Bioavailability of Drug Formula Elements

Variables

Bioavailability of Drug

The Bioavailability of Drug is defined as the systemically available fraction of a drug.

Symbol: f

Measurement: NAUnit: Unitless

Note: Value can be positive or negative.

Formulas to find Bioavailability of Drug

Area under Curve Non-Intravenous

The Area under Curve Non-Intravenous is the integral of the concentration-time curve after a single dose is administered orally.

Symbol: AUC_po

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value should be greater than 0.

Formulas to find Area under Curve Non-Intravenous

Dose Intravenous

The Dose Intravenous is the amount of drug administered intravenously.

Symbol: D_iv

Measurement: Amount of SubstanceUnit: mol

Note: Value should be greater than 0.

Formulas to find Dose Intravenous

Area under Curve Intravenous

Area under Curve Intravenous is the integral of the concentration-time curve after a single dose administered intravenous.

Symbol: AUC_iv

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value can be positive or negative.

Formulas to find Area under Curve Intravenous

Dose Non-Intravenous

The Dose Non-Intravenous is the amount of drug administered orally.

Symbol: D_po

Measurement: Amount of SubstanceUnit: mol

Note: Value should be greater than 0.

Formulas to find Dose Non-Intravenous

Other formulas in Bioavailability category

Go Bioavailability given Effective and Administrative Dose

B = \frac{D e}{D a}

Go Bioavailability given Drug Purity

B = \frac{D e}{Q \cdot D a}

Go Bioavailability given Rate of Administration and Dosing Interval

B = \frac{V a \cdot Τ}{D a \cdot Q}

How to Evaluate Bioavailability of Drug?

Bioavailability of Drug evaluator uses Bioavailability of Drug = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Dose Non-Intravenous) to evaluate the Bioavailability of Drug, The Bioavailability of drug formula is defined as the comparison the bioavailability of the active drug in systemic circulation following non-intravenous administration to the bioavailability of the same drug following intravenous administration. Bioavailability of Drug is denoted by f symbol.

How to evaluate Bioavailability of Drug using this online evaluator? To use this online evaluator for Bioavailability of Drug, enter Area under Curve Non-Intravenous (AUC_po), Dose Intravenous (D_iv), Area under Curve Intravenous (AUC_iv) & Dose Non-Intravenous (D_po) and hit the calculate button.

FAQs on Bioavailability of Drug

What is the formula to find Bioavailability of Drug?

The formula of Bioavailability of Drug is expressed as Bioavailability of Drug = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Dose Non-Intravenous). Here is an example- 1.636364 = (6000*12)/(11000*4).

How to calculate Bioavailability of Drug?

With Area under Curve Non-Intravenous (AUC_po), Dose Intravenous (D_iv), Area under Curve Intravenous (AUC_iv) & Dose Non-Intravenous (D_po) we can find Bioavailability of Drug using the formula - Bioavailability of Drug = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Dose Non-Intravenous).

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Bioavailability of Drug Formula

Bioavailability of Drug Example

Bioavailability of Drug Solution

Bioavailability of Drug Formula Elements

Other formulas in Bioavailability category

How to Evaluate Bioavailability of Drug?

FAQs on Bioavailability of Drug

Variable Name