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Average Concentration of Plasma at Steady State Formula

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Average Concentration of Plasma at Steady State is the amount of a drug in a given volume of blood plasma of the sample. Check FAQs

c̅p ss = \frac{D}{CL \cdot Τ}

c̅p_ss - Average Concentration of Plasma at Steady State?D - Dose?CL - Volume of Plasma Cleared?Τ - Dosing Interval?

Average Concentration of Plasma at Steady State Example

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Here is how the Average Concentration of Plasma at Steady State equation looks like with Values.

Here is how the Average Concentration of Plasma at Steady State equation looks like with Units.

Here is how the Average Concentration of Plasma at Steady State equation looks like.

0.3788 = \frac{8}{0.48 \cdot 44}

0.3788mol/L = \frac{8mol}{0.48L/s \cdot 44s}

0.3788 = \frac{8}{0.48 \cdot 44}

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Average Concentration of Plasma at Steady State Solution

Follow our step by step solution on how to calculate Average Concentration of Plasma at Steady State?

FIRST Step Consider the formula

c̅p ss = \frac{D}{CL \cdot Τ}

Next Step Substitute values of Variables

∴

c̅p ss = \frac{8mol}{0.48L/s \cdot 44s}

Next Step Convert Units

∴

c̅p ss = \frac{8mol}{0.0005m³/s \cdot 44s}

Next Step Prepare to Evaluate

∴

c̅p ss = \frac{8}{0.0005 \cdot 44}

Next Step Evaluate

∴

c̅p ss = 378.787878787879mol/m³

Next Step Convert to Output's Unit

∴

c̅p ss = 0.378787878787879mol/L

LAST Step Rounding Answer

∴

c̅p ss = 0.3788mol/L

Average Concentration of Plasma at Steady State Formula Elements

Variables

Average Concentration of Plasma at Steady State

Average Concentration of Plasma at Steady State is the amount of a drug in a given volume of blood plasma of the sample.

Symbol: c̅p_ss

Measurement: Molar ConcentrationUnit: mol/L

Note: Value should be greater than 0.

Formulas to find Average Concentration of Plasma at Steady State

Dose

The Dose is the amount of drug administered.

Symbol: D

Measurement: Amount of SubstanceUnit: mol

Note: Value can be positive or negative.

Formulas to find Dose

Volume of Plasma Cleared

The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.

Symbol: CL

Measurement: Volumetric Flow RateUnit: L/s

Note: Value can be positive or negative.

Formulas to find Volume of Plasma Cleared

Dosing Interval

The Dosing Interval is the time between drug dose administrations.

Symbol: Τ

Measurement: TimeUnit: s

Note: Value can be positive or negative.

Formulas to find Dosing Interval

Other formulas in Plasma category

Go Plasma Volume of Drug given Apparent Volume

V P = V d - (V T \cdot (\frac{fu}{fu t}))

Go Apparent Tissue Volume given Plasma Volume and Apparent Volume

V T = (V d - V P) \cdot (\frac{fu t}{fu})

Go Peak through Fluctuation

%PTF = \frac{C max - C min}{C av}

Go Peak Plasma Concentration Given Peak through Fluctuation

C max = (%PTF \cdot C av) + C min

How to Evaluate Average Concentration of Plasma at Steady State?

Average Concentration of Plasma at Steady State evaluator uses Average Concentration of Plasma at Steady State = Dose/(Volume of Plasma Cleared*Dosing Interval) to evaluate the Average Concentration of Plasma at Steady State, The Average Concentration of Plasma at Steady State formula is defined as the concentration of an agent in the plasma which is derived from full blood. Plasma concentrations are used to define major PK and PK/PD parameters. Average Concentration of Plasma at Steady State is denoted by c̅p_ss symbol.

How to evaluate Average Concentration of Plasma at Steady State using this online evaluator? To use this online evaluator for Average Concentration of Plasma at Steady State, enter Dose (D), Volume of Plasma Cleared (CL) & Dosing Interval (Τ) and hit the calculate button.

FAQs on Average Concentration of Plasma at Steady State

What is the formula to find Average Concentration of Plasma at Steady State?

The formula of Average Concentration of Plasma at Steady State is expressed as Average Concentration of Plasma at Steady State = Dose/(Volume of Plasma Cleared*Dosing Interval). Here is an example- 0.000379 = 8/(0.00048*44).

How to calculate Average Concentration of Plasma at Steady State?

With Dose (D), Volume of Plasma Cleared (CL) & Dosing Interval (Τ) we can find Average Concentration of Plasma at Steady State using the formula - Average Concentration of Plasma at Steady State = Dose/(Volume of Plasma Cleared*Dosing Interval).

Can the Average Concentration of Plasma at Steady State be negative?

No, the Average Concentration of Plasma at Steady State, measured in Molar Concentration cannot be negative.

Which unit is used to measure Average Concentration of Plasma at Steady State?

Average Concentration of Plasma at Steady State is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Average Concentration of Plasma at Steady State can be measured.

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Average Concentration of Plasma at Steady State Formula

Average Concentration of Plasma at Steady State Example

Average Concentration of Plasma at Steady State Solution

Average Concentration of Plasma at Steady State Formula Elements

Other formulas in Plasma category

How to Evaluate Average Concentration of Plasma at Steady State?

FAQs on Average Concentration of Plasma at Steady State

Variable Name