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Area under Curve for Drug Administered Orally Formula

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The Area under Curve Non-Intravenous is the integral of the concentration-time curve after a single dose is administered orally. Check FAQs

AUC po = \frac{f \cdot AUC iv \cdot D po}{D iv}

AUC_po - Area under Curve Non-Intravenous?f - Bioavailability of Drug?AUC_iv - Area under Curve Intravenous?D_po - Dose Non-Intravenous?D_iv - Dose Intravenous?

Area under Curve for Drug Administered Orally Example

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Here is how the Area under Curve for Drug Administered Orally equation looks like with Values.

Here is how the Area under Curve for Drug Administered Orally equation looks like with Units.

Here is how the Area under Curve for Drug Administered Orally equation looks like.

34.8333 = \frac{9.5 \cdot 11 \cdot 4}{12}

34.8333mol*s/L = \frac{9.5 \cdot 11mol*s/L \cdot 4mol}{12mol}

34.8333 = \frac{9.5 \cdot 11 \cdot 4}{12}

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Area under Curve for Drug Administered Orally Solution

Follow our step by step solution on how to calculate Area under Curve for Drug Administered Orally?

FIRST Step Consider the formula

AUC po = \frac{f \cdot AUC iv \cdot D po}{D iv}

Next Step Substitute values of Variables

∴

AUC po = \frac{9.5 \cdot 11mol*s/L \cdot 4mol}{12mol}

Next Step Convert Units

∴

AUC po = \frac{9.5 \cdot 11000mol*s/m³ \cdot 4mol}{12mol}

Next Step Prepare to Evaluate

∴

AUC po = \frac{9.5 \cdot 11000 \cdot 4}{12}

Next Step Evaluate

∴

AUC po = 34833.3333333333mol*s/m³

Next Step Convert to Output's Unit

∴

AUC po = 34.8333333333333mol*s/L

LAST Step Rounding Answer

∴

AUC po = 34.8333mol*s/L

Area under Curve for Drug Administered Orally Formula Elements

Variables

Area under Curve Non-Intravenous

The Area under Curve Non-Intravenous is the integral of the concentration-time curve after a single dose is administered orally.

Symbol: AUC_po

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value should be greater than 0.

Formulas to find Area under Curve Non-Intravenous

Bioavailability of Drug

The Bioavailability of Drug is defined as the systemically available fraction of a drug.

Symbol: f

Measurement: NAUnit: Unitless

Note: Value can be positive or negative.

Formulas to find Bioavailability of Drug

Area under Curve Intravenous

Area under Curve Intravenous is the integral of the concentration-time curve after a single dose administered intravenous.

Symbol: AUC_iv

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value can be positive or negative.

Formulas to find Area under Curve Intravenous

Dose Non-Intravenous

The Dose Non-Intravenous is the amount of drug administered orally.

Symbol: D_po

Measurement: Amount of SubstanceUnit: mol

Note: Value should be greater than 0.

Formulas to find Dose Non-Intravenous

Dose Intravenous

The Dose Intravenous is the amount of drug administered intravenously.

Symbol: D_iv

Measurement: Amount of SubstanceUnit: mol

Note: Value should be greater than 0.

Formulas to find Dose Intravenous

Other formulas in Area under curve category

Go Area under Curve given Volume of Plasma Cleared

AUC = \frac{D}{CL}

Go Area under Curve given Dose and Volume of Distribution

AUC = \frac{D}{V d \cdot k e}

Go Area under Curve for Drug Administered Intravenous

AUC iv = \frac{AUC po \cdot D iv}{f \cdot D po}

Go Area under Curve of Drug for Dosage Type A

AUC dosageA = (F rel \cdot AUC dosageB) \cdot (\frac{D A}{D B})

How to Evaluate Area under Curve for Drug Administered Orally?

Area under Curve for Drug Administered Orally evaluator uses Area under Curve Non-Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Dose Intravenous to evaluate the Area under Curve Non-Intravenous, The Area under Curve for Drug Administered Orally formula is defined as the comparison the bioavailability of the active drug in systemic circulation following non-intravenous administration to the bioavailability of the same drug following intravenous administration. Area under Curve Non-Intravenous is denoted by AUC_po symbol.

How to evaluate Area under Curve for Drug Administered Orally using this online evaluator? To use this online evaluator for Area under Curve for Drug Administered Orally, enter Bioavailability of Drug (f), Area under Curve Intravenous (AUC_iv), Dose Non-Intravenous (D_po) & Dose Intravenous (D_iv) and hit the calculate button.

FAQs on Area under Curve for Drug Administered Orally

What is the formula to find Area under Curve for Drug Administered Orally?

The formula of Area under Curve for Drug Administered Orally is expressed as Area under Curve Non-Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Dose Intravenous. Here is an example- 0.034833 = (9.5*11000*4)/12.

How to calculate Area under Curve for Drug Administered Orally?

With Bioavailability of Drug (f), Area under Curve Intravenous (AUC_iv), Dose Non-Intravenous (D_po) & Dose Intravenous (D_iv) we can find Area under Curve for Drug Administered Orally using the formula - Area under Curve Non-Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Dose Intravenous.

Can the Area under Curve for Drug Administered Orally be negative?

No, the Area under Curve for Drug Administered Orally, measured in Concentration Time Coefficient cannot be negative.

Which unit is used to measure Area under Curve for Drug Administered Orally?

Area under Curve for Drug Administered Orally is usually measured using the Mole Second per Liter[mol*s/L] for Concentration Time Coefficient. Mole Second per Cubic Meter[mol*s/L], Mole second per Milliliter[mol*s/L] are the few other units in which Area under Curve for Drug Administered Orally can be measured.

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Area under Curve for Drug Administered Orally Formula

Area under Curve for Drug Administered Orally Example

Area under Curve for Drug Administered Orally Solution

Area under Curve for Drug Administered Orally Formula Elements

Other formulas in Area under curve category

How to Evaluate Area under Curve for Drug Administered Orally?

FAQs on Area under Curve for Drug Administered Orally

Variable Name