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Area under Curve for Drug Administered Intravenous Formula

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Area under Curve Intravenous is the integral of the concentration-time curve after a single dose administered intravenous. Check FAQs

AUC iv = \frac{AUC po \cdot D iv}{f \cdot D po}

AUC_iv - Area under Curve Intravenous?AUC_po - Area under Curve Non-Intravenous?D_iv - Dose Intravenous?f - Bioavailability of Drug?D_po - Dose Non-Intravenous?

Area under Curve for Drug Administered Intravenous Example

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Here is how the Area under Curve for Drug Administered Intravenous equation looks like with Values.

Here is how the Area under Curve for Drug Administered Intravenous equation looks like with Units.

Here is how the Area under Curve for Drug Administered Intravenous equation looks like.

1.8947 = \frac{6 \cdot 12}{9.5 \cdot 4}

1.8947mol*s/L = \frac{6mol*s/L \cdot 12mol}{9.5 \cdot 4mol}

1.8947 = \frac{6 \cdot 12}{9.5 \cdot 4}

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Area under Curve for Drug Administered Intravenous Solution

Follow our step by step solution on how to calculate Area under Curve for Drug Administered Intravenous?

FIRST Step Consider the formula

AUC iv = \frac{AUC po \cdot D iv}{f \cdot D po}

Next Step Substitute values of Variables

∴

AUC iv = \frac{6mol*s/L \cdot 12mol}{9.5 \cdot 4mol}

Next Step Convert Units

∴

AUC iv = \frac{6000mol*s/m³ \cdot 12mol}{9.5 \cdot 4mol}

Next Step Prepare to Evaluate

∴

AUC iv = \frac{6000 \cdot 12}{9.5 \cdot 4}

Next Step Evaluate

∴

AUC iv = 1894.73684210526mol*s/m³

Next Step Convert to Output's Unit

∴

AUC iv = 1.89473684210526mol*s/L

LAST Step Rounding Answer

∴

AUC iv = 1.8947mol*s/L

Area under Curve for Drug Administered Intravenous Formula Elements

Variables

Area under Curve Intravenous

Area under Curve Intravenous is the integral of the concentration-time curve after a single dose administered intravenous.

Symbol: AUC_iv

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value can be positive or negative.

Formulas to find Area under Curve Intravenous

Area under Curve Non-Intravenous

The Area under Curve Non-Intravenous is the integral of the concentration-time curve after a single dose is administered orally.

Symbol: AUC_po

Measurement: Concentration Time CoefficientUnit: mol*s/L

Note: Value should be greater than 0.

Formulas to find Area under Curve Non-Intravenous

Dose Intravenous

The Dose Intravenous is the amount of drug administered intravenously.

Symbol: D_iv

Measurement: Amount of SubstanceUnit: mol

Note: Value should be greater than 0.

Formulas to find Dose Intravenous

Bioavailability of Drug

The Bioavailability of Drug is defined as the systemically available fraction of a drug.

Symbol: f

Measurement: NAUnit: Unitless

Note: Value can be positive or negative.

Formulas to find Bioavailability of Drug

Dose Non-Intravenous

The Dose Non-Intravenous is the amount of drug administered orally.

Symbol: D_po

Measurement: Amount of SubstanceUnit: mol

Note: Value should be greater than 0.

Formulas to find Dose Non-Intravenous

Other formulas in Area under curve category

Go Area under Curve given Volume of Plasma Cleared

AUC = \frac{D}{CL}

Go Area under Curve given Dose and Volume of Distribution

AUC = \frac{D}{V d \cdot k e}

Go Area under Curve for Drug Administered Orally

AUC po = \frac{f \cdot AUC iv \cdot D po}{D iv}

Go Area under Curve of Drug for Dosage Type A

AUC dosageA = (F rel \cdot AUC dosageB) \cdot (\frac{D A}{D B})

How to Evaluate Area under Curve for Drug Administered Intravenous?

Area under Curve for Drug Administered Intravenous evaluator uses Area under Curve Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Bioavailability of Drug*Dose Non-Intravenous) to evaluate the Area under Curve Intravenous, The Area under Curve for Drug Administered Intravenous formula is defined as the comparison of the bioavailability of the active drug in systemic circulation following non-intravenous administration to the bioavailability of the same drug following intravenous administration. Area under Curve Intravenous is denoted by AUC_iv symbol.

How to evaluate Area under Curve for Drug Administered Intravenous using this online evaluator? To use this online evaluator for Area under Curve for Drug Administered Intravenous, enter Area under Curve Non-Intravenous (AUC_po), Dose Intravenous (D_iv), Bioavailability of Drug (f) & Dose Non-Intravenous (D_po) and hit the calculate button.

FAQs on Area under Curve for Drug Administered Intravenous

What is the formula to find Area under Curve for Drug Administered Intravenous?

The formula of Area under Curve for Drug Administered Intravenous is expressed as Area under Curve Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Bioavailability of Drug*Dose Non-Intravenous). Here is an example- 0.001895 = (6000*12)/(9.5*4).

How to calculate Area under Curve for Drug Administered Intravenous?

With Area under Curve Non-Intravenous (AUC_po), Dose Intravenous (D_iv), Bioavailability of Drug (f) & Dose Non-Intravenous (D_po) we can find Area under Curve for Drug Administered Intravenous using the formula - Area under Curve Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Bioavailability of Drug*Dose Non-Intravenous).

Can the Area under Curve for Drug Administered Intravenous be negative?

Yes, the Area under Curve for Drug Administered Intravenous, measured in Concentration Time Coefficient can be negative.

Which unit is used to measure Area under Curve for Drug Administered Intravenous?

Area under Curve for Drug Administered Intravenous is usually measured using the Mole Second per Liter[mol*s/L] for Concentration Time Coefficient. Mole Second per Cubic Meter[mol*s/L], Mole second per Milliliter[mol*s/L] are the few other units in which Area under Curve for Drug Administered Intravenous can be measured.

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Area under Curve for Drug Administered Intravenous Formula

Area under Curve for Drug Administered Intravenous Example

Area under Curve for Drug Administered Intravenous Solution

Area under Curve for Drug Administered Intravenous Formula Elements

Other formulas in Area under curve category

How to Evaluate Area under Curve for Drug Administered Intravenous?

FAQs on Area under Curve for Drug Administered Intravenous

Variable Name