Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition Formula

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The Apparent Michaelis Constant is defined as the Michaelis–Menten constant in the presence of a competitive inhibitor. Check FAQs
Kmapp=S(Vmax-V0)V0
Kmapp - Apparent Michaelis Constant?S - Substrate Concentration?Vmax - Maximum Rate?V0 - Initial Reaction Rate?

Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition Example

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Here is how the Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition equation looks like with Values.

Here is how the Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition equation looks like with Units.

Here is how the Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition equation looks like.

131.8333Edit=1.5Edit(40Edit-0.45Edit)0.45Edit
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Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition Solution

Follow our step by step solution on how to calculate Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition?

FIRST Step Consider the formula
Kmapp=S(Vmax-V0)V0
Next Step Substitute values of Variables
Kmapp=1.5mol/L(40mol/L*s-0.45mol/L*s)0.45mol/L*s
Next Step Convert Units
Kmapp=1500mol/m³(40000mol/m³*s-450mol/m³*s)450mol/m³*s
Next Step Prepare to Evaluate
Kmapp=1500(40000-450)450
Next Step Evaluate
Kmapp=131833.333333333mol/m³
Next Step Convert to Output's Unit
Kmapp=131.833333333333mol/L
LAST Step Rounding Answer
Kmapp=131.8333mol/L

Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition Formula Elements

Variables
Apparent Michaelis Constant
The Apparent Michaelis Constant is defined as the Michaelis–Menten constant in the presence of a competitive inhibitor.
Symbol: Kmapp
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Substrate Concentration
The Substrate Concentration is the number of moles of substrate per liter solution.
Symbol: S
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Maximum Rate
The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Symbol: Vmax
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.
Initial Reaction Rate
The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Symbol: V0
Measurement: Reaction RateUnit: mol/L*s
Note: Value can be positive or negative.

Other formulas in Competitive Inhibitor category

​Go Substrate Concentration of Competitive Inhibition of Enzyme Catalysis
S=V0(KM(1+(IKi)))(k2[E0])-V0
​Go Substrate Concentration in Competitive Inhibition given Maximum Rate of System
S=V0(KM(1+(IKi)))Vmax-V0
​Go Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration
S=ES(KM(1+(IKi)))([E0])-ES
​Go Substrate Concentration given Apparent value of Michaelis Menten Constant
S=KmappV0Vmax-V0

How to Evaluate Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition?

Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition evaluator uses Apparent Michaelis Constant = (Substrate Concentration*(Maximum Rate-Initial Reaction Rate))/Initial Reaction Rate to evaluate the Apparent Michaelis Constant, The Apparent value of Michaelis Menten constant in presence of Competitive inhibition formula is defined as a plot of the reaction velocity (V0) associated with the concentration [S] of the substrate can then be used to determine values such as Vmax, initial velocity, and Km(app). Apparent Michaelis Constant is denoted by Kmapp symbol.

How to evaluate Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition using this online evaluator? To use this online evaluator for Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition, enter Substrate Concentration (S), Maximum Rate (Vmax) & Initial Reaction Rate (V0) and hit the calculate button.

FAQs on Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition

What is the formula to find Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition?
The formula of Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition is expressed as Apparent Michaelis Constant = (Substrate Concentration*(Maximum Rate-Initial Reaction Rate))/Initial Reaction Rate. Here is an example- 0.131833 = (1500*(40000-450))/450.
How to calculate Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition?
With Substrate Concentration (S), Maximum Rate (Vmax) & Initial Reaction Rate (V0) we can find Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition using the formula - Apparent Michaelis Constant = (Substrate Concentration*(Maximum Rate-Initial Reaction Rate))/Initial Reaction Rate.
Can the Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition be negative?
Yes, the Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition, measured in Molar Concentration can be negative.
Which unit is used to measure Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition?
Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition can be measured.
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