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Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant Formula

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The Apparent Michaelis Constant is defined as the Michaelis–Menten constant in the presence of a competitive inhibitor. Check FAQs

Km app = K M \cdot (1 + (\frac{I}{K i}))

Km^app - Apparent Michaelis Constant?K_M - Michaelis Constant?I - Inhibitor Concentration?K_i - Enzyme Inhibitor Dissociation Constant?

Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant Example

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Here is how the Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant equation looks like with Values.

Here is how the Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant equation looks like with Units.

Here is how the Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant equation looks like.

4.4211 = 3 \cdot (1 + (\frac{9}{19}))

4.4211mol/L = 3mol/L \cdot (1 + (\frac{9mol/L}{19mol/L}))

4.4211 = 3 \cdot (1 + (\frac{9}{19}))

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Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant Solution

Follow our step by step solution on how to calculate Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant?

FIRST Step Consider the formula

Km app = K M \cdot (1 + (\frac{I}{K i}))

Next Step Substitute values of Variables

∴

Km app = 3mol/L \cdot (1 + (\frac{9mol/L}{19mol/L}))

Next Step Convert Units

∴

Km app = 3000mol/m³ \cdot (1 + (\frac{9000mol/m³}{19000mol/m³}))

Next Step Prepare to Evaluate

∴

Km app = 3000 \cdot (1 + (\frac{9000}{19000}))

Next Step Evaluate

∴

Km app = 4421.05263157895mol/m³

Next Step Convert to Output's Unit

∴

Km app = 4.42105263157895mol/L

LAST Step Rounding Answer

∴

Km app = 4.4211mol/L

Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant Formula Elements

Variables

Apparent Michaelis Constant

The Apparent Michaelis Constant is defined as the Michaelis–Menten constant in the presence of a competitive inhibitor.

Symbol: Km^app

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Apparent Michaelis Constant

Michaelis Constant

The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.

Symbol: K_M

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Michaelis Constant

Inhibitor Concentration

The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.

Symbol: I

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Inhibitor Concentration

Enzyme Inhibitor Dissociation Constant

The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

Symbol: K_i

Measurement: Molar ConcentrationUnit: mol/L

Note: Value can be positive or negative.

Formulas to find Enzyme Inhibitor Dissociation Constant

Other formulas in Noncompetitive Inhibitor category

Go Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor

E0 app = (\frac{[E 0]}{1 + (\frac{I}{K i})})

Go Apparent Maximum Rate in presence of Noncompetitive Inhibitor

Vmax app = (\frac{V max}{1 + (\frac{I}{K i})})

Go Dissociation Constant given Apparent Initial Enzyme Concentration

K i = (\frac{I}{(\frac{[E 0]}{E0 app}) - 1})

Go Dissociation Constant given Enzyme Substrate Complex Concentration

K i = \frac{I}{(\frac{(\frac{[E 0] \cdot S}{ES}) - S}{K M}) - 1}

How to Evaluate Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant?

Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant evaluator uses Apparent Michaelis Constant = Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant)) to evaluate the Apparent Michaelis Constant, The Apparent Michaelis Menten constant given inhibitor's dissociation constant formula is defined as the relation with inhibitor's dissociation constant and with the inhibitor concentration. Apparent Michaelis Constant is denoted by Km^app symbol.

How to evaluate Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant using this online evaluator? To use this online evaluator for Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant, enter Michaelis Constant (K_M), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (K_i) and hit the calculate button.

FAQs on Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant

What is the formula to find Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant?

The formula of Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant is expressed as Apparent Michaelis Constant = Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant)). Here is an example- 0.004421 = 3000*(1+(9000/19000)).

How to calculate Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant?

With Michaelis Constant (K_M), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (K_i) we can find Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant using the formula - Apparent Michaelis Constant = Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant)).

Can the Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant be negative?

Yes, the Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant, measured in Molar Concentration can be negative.

Which unit is used to measure Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant?

Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant can be measured.

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Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant Formula

Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant Example

Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant Solution

Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant Formula Elements

Other formulas in Noncompetitive Inhibitor category

How to Evaluate Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant?

FAQs on Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant

Variable Name