Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor Formula

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The Apparent Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction in the presence of a non-competitive inhibitor. Check FAQs
E0app=([E0]1+(IKi))
E0app - Apparent Initial Enzyme Concentration?[E0] - Initial Enzyme Concentration?I - Inhibitor Concentration?Ki - Enzyme Inhibitor Dissociation Constant?

Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor Example

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Here is how the Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor equation looks like with Values.

Here is how the Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor equation looks like with Units.

Here is how the Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor equation looks like.

67.8571Edit=(100Edit1+(9Edit19Edit))
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Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor Solution

Follow our step by step solution on how to calculate Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor?

FIRST Step Consider the formula
E0app=([E0]1+(IKi))
Next Step Substitute values of Variables
E0app=(100mol/L1+(9mol/L19mol/L))
Next Step Convert Units
E0app=(100000mol/m³1+(9000mol/m³19000mol/m³))
Next Step Prepare to Evaluate
E0app=(1000001+(900019000))
Next Step Evaluate
E0app=67857.1428571429mol/m³
Next Step Convert to Output's Unit
E0app=67.8571428571429mol/L
LAST Step Rounding Answer
E0app=67.8571mol/L

Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor Formula Elements

Variables
Apparent Initial Enzyme Concentration
The Apparent Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction in the presence of a non-competitive inhibitor.
Symbol: E0app
Measurement: Molar ConcentrationUnit: mol/L
Note: Value should be greater than 0.
Initial Enzyme Concentration
The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.
Symbol: [E0]
Measurement: Molar ConcentrationUnit: mol/L
Note: Value should be greater than 0.
Inhibitor Concentration
The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Symbol: I
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.
Enzyme Inhibitor Dissociation Constant
The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.
Symbol: Ki
Measurement: Molar ConcentrationUnit: mol/L
Note: Value can be positive or negative.

Other formulas in Noncompetitive Inhibitor category

​Go Apparent Maximum Rate in presence of Noncompetitive Inhibitor
Vmaxapp=(Vmax1+(IKi))
​Go Apparent Michaelis Menten constant given Inhibitor's Dissociation Constant
Kmapp=KM(1+(IKi))
​Go Dissociation Constant given Apparent Initial Enzyme Concentration
Ki=(I([E0]E0app)-1)
​Go Dissociation Constant given Enzyme Substrate Complex Concentration
Ki=I(([E0]SES)-SKM)-1

How to Evaluate Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor?

Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor evaluator uses Apparent Initial Enzyme Concentration = (Initial Enzyme Concentration/(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))) to evaluate the Apparent Initial Enzyme Concentration, The Apparent initial enzyme concentration in presence of noncompetitive inhibitor formula is defined as relation to the initial enzyme concentration, inhibitor concentration, and dissociation constant. Apparent Initial Enzyme Concentration is denoted by E0app symbol.

How to evaluate Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor using this online evaluator? To use this online evaluator for Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor, enter Initial Enzyme Concentration ([E0]), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (Ki) and hit the calculate button.

FAQs on Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor

What is the formula to find Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor?
The formula of Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor is expressed as Apparent Initial Enzyme Concentration = (Initial Enzyme Concentration/(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))). Here is an example- 0.067857 = (100000/(1+(9000/19000))).
How to calculate Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor?
With Initial Enzyme Concentration ([E0]), Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (Ki) we can find Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor using the formula - Apparent Initial Enzyme Concentration = (Initial Enzyme Concentration/(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))).
Can the Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor be negative?
No, the Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor, measured in Molar Concentration cannot be negative.
Which unit is used to measure Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor?
Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor is usually measured using the Mole per Liter[mol/L] for Molar Concentration. Mole per Cubic Meter[mol/L], Mole per Cubic Millimeter[mol/L], Kilomole per Cubic Meter[mol/L] are the few other units in which Apparent Initial Enzyme Concentration in Presence of Noncompetitive Inhibitor can be measured.
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