Drug Clearance in Pharmacokinetics Formulas

Drug Clearance is the rate at which a drug or its metabolites are removed from the body and systemic circulation. And is denoted by CL_drug. Drug Clearance is usually measured using the Cubic Meter per Second for Volumetric Flow Rate. Note that the value of Drug Clearance is always negative.

Formulas to find Drug Clearance in Pharmacokinetics

fxClearance of Drug given Maintenance DoseGo

Pharmacokinetics formulas that make use of Drug Clearance

fxMaintenance DoseGo

fxTarget Plasma Concentration given Maintenance DoseGo

fxBioavailability of Drug given Maintenance DoseGo

List of variables in Pharmacokinetics formulas

fx Maintenance Dose Go

fx Bioavailability of Drug Go

fx Target Plasma Concentration Go

FAQ

What is the Drug Clearance?

Drug Clearance is the rate at which a drug or its metabolites are removed from the body and systemic circulation. Drug Clearance is usually measured using the Cubic Meter per Second for Volumetric Flow Rate. Note that the value of Drug Clearance is always negative.

Can the Drug Clearance be negative?

Yes, the Drug Clearance, measured in Volumetric Flow Rate can be negative.

What unit is used to measure Drug Clearance?

Drug Clearance is usually measured using the Cubic Meter per Second[m³/s] for Volumetric Flow Rate. Cubic Meter per Day[m³/s], Cubic Meter per Hour[m³/s], Cubic Meter per Minute[m³/s] are the few other units in which Drug Clearance can be measured.

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