Area Under Curve in Pharmacokinetics Formulas

Area under Curve (AUC) is the definite integral of a curve that describes the variation of a drug concentration in blood plasma as a function of time. And is denoted by AUC. Area Under Curve is usually measured using the Mole Second per Liter for Concentration Time Coefficient. Note that the value of Area Under Curve is always negative.

Formulas to find Area Under Curve in Pharmacokinetics

fxArea under Curve given Volume of Plasma ClearedGo

fxArea under Curve given Dose and Volume of DistributionGo

fxArea under Curve Given Average Plasma ConcentrationGo

Pharmacokinetics formulas that make use of Area Under Curve

fxAmount of drug administered given area under curveGo

fxDose given volume of distribution and area under curveGo

fxDosing interval given average plasma concentrationGo

fxAverage Plasma Concentration given Area under CurveGo

fxVolume of Distribution given Area under CurveGo

fxVolume of Plasma Cleared given Area under CurveGo

fxElimination Rate Constant given Area under CurveGo

fxRenal Clearance of DrugGo

List of variables in Pharmacokinetics formulas

fx Dose Go

fx Volume of Plasma Cleared Go

fx Volume of Distribution Go

fx Elimination Rate Constant Go

fx Average Plasma Concentration Go

fx Dosing Interval Go

FAQ

What is the Area Under Curve?

Area under Curve (AUC) is the definite integral of a curve that describes the variation of a drug concentration in blood plasma as a function of time. Area Under Curve is usually measured using the Mole Second per Liter for Concentration Time Coefficient. Note that the value of Area Under Curve is always negative.

Can the Area Under Curve be negative?

Yes, the Area Under Curve, measured in Concentration Time Coefficient can be negative.

What unit is used to measure Area Under Curve?

Area Under Curve is usually measured using the Mole Second per Liter[mol*s/L] for Concentration Time Coefficient. Mole Second per Cubic Meter[mol*s/L], Mole second per Milliliter[mol*s/L] are the few other units in which Area Under Curve can be measured.

Let Others Know

✖

Facebook

Twitter

Copied!